Evidence map›Paper›PMID 34040729›Full record

ArticleChemical science2021

An intramolecular photoswitch can significantly promote photoactivation of Pt(iv) prodrugs.

Zhiqin Deng, Cai Li, Shu Chen, Qiyuan Zhou, Zoufeng Xu, Zhigang Wang, Houzong Yao, Hajime Hirao, Guangyu Zhu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Recent Advances in Light-Controlled Activation of Pt(IV) Prodrugs.International journal of molecular sciences · 2022
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Zhiqin DengDepartment of Chemistry, City University of Hong Kong Hong Kong SAR P. R. China guangzhu@cityu.edu.hk.ORCID https://orcid.org/0000-0002-2852-2009
Cai LiDepartment of Chemistry, City University of Hong Kong Hong Kong SAR P. R. China guangzhu@cityu.edu.hk.
Shu ChenDepartment of Chemistry, City University of Hong Kong Hong Kong SAR P. R. China guangzhu@cityu.edu.hk.
Qiyuan ZhouDepartment of Chemistry, City University of Hong Kong Hong Kong SAR P. R. China guangzhu@cityu.edu.hk.
Zoufeng XuDepartment of Chemistry, City University of Hong Kong Hong Kong SAR P. R. China guangzhu@cityu.edu.hk.
Zhigang WangSchool of Pharmaceutical Sciences, Health Science Center, Shenzhen University Shenzhen P. R. China.
Houzong YaoDepartment of Chemistry, City University of Hong Kong Hong Kong SAR P. R. China guangzhu@cityu.edu.hk.
Hajime HiraoDepartment of Chemistry, City University of Hong Kong Hong Kong SAR P. R. China guangzhu@cityu.edu.hk.ORCID https://orcid.org/0000-0002-8239-3471
Guangyu ZhuDepartment of Chemistry, City University of Hong Kong Hong Kong SAR P. R. China guangzhu@cityu.edu.hk.ORCID https://orcid.org/0000-0002-4710-7070
City University of Hong Kong · HKShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selective activation of prodrugs at diseased tissue through bioorthogonal catalysis represents an attractive strategy for precision cancer treatment. Achieving efficient prodrug photoactivation in cancer cells, however, remains challenging. Herein, we report two Pt(iv) complexes, designated as rhodaplatins {rhodaplatin

Identifiers

PMID34040729
PMCPMC8139284
OpenAlexW3152121126

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.