Evidence map›Paper›PMID 34040721›Full record

ArticleChemical science2019

Disruption of microtubule function in cultured human cells by a cytotoxic ruthenium(ii) polypyridyl complex.

Nagham Alatrash, Faiza H Issa, Nada S Bawazir, Savannah J West, Kathleen E Van Manen-Brush, Charles P Shelor, Adam S Dayoub, Kenneth A Myers, Christopher Janetopoulos, Edwin A Lewis and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Exploring the Potential of Metal-Based Candidate Drugs as Modulators of the Cytoskeleton.Chembiochem : a European journal of chemical biology · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Nagham AlatrashDepartment of Chemistry and Biochemistry, University of Texas at Arlington Arlington TX 76019 USA macdonn@uta.edu.
Faiza H IssaDepartment of Chemistry and Biochemistry, University of Texas at Arlington Arlington TX 76019 USA macdonn@uta.edu.
Nada S BawazirDepartment of Biological Sciences, University of the Sciences Philadelphia PA 19104 USA.
Savannah J WestDepartment of Chemistry, Mississippi State University Starkville MS 39762 USA.
Kathleen E Van Manen-BrushDepartment of Biological Sciences, University of the Sciences Philadelphia PA 19104 USA.
Charles P ShelorDepartment of Chemistry and Biochemistry, University of Texas at Arlington Arlington TX 76019 USA macdonn@uta.edu.
Adam S DayoubDepartment of Chemistry and Biochemistry, University of Texas at Arlington Arlington TX 76019 USA macdonn@uta.edu.
Kenneth A MyersDepartment of Biological Sciences, University of the Sciences Philadelphia PA 19104 USA.
Christopher JanetopoulosDepartment of Biological Sciences, University of the Sciences Philadelphia PA 19104 USA.
Edwin A LewisDepartment of Chemistry, Mississippi State University Starkville MS 39762 USA.
Frederick M MacDonnellDepartment of Chemistry and Biochemistry, University of Texas at Arlington Arlington TX 76019 USA macdonn@uta.edu.ORCID https://orcid.org/0000-0002-6678-3939
The University of Texas at Arlington · USUniversity of the Sciences · USStark State College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of malignant and non-malignant cultured human cell lines with a cytotoxic IC

Identifiers

PMID34040721
PMCPMC8133002
OpenAlexW2985210665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.