Evidence map›Paper›PMID 34040717›Full record

ArticleChemical science2019

Isothiourea-catalysed enantioselective Michael addition of N-heterocyclic pronucleophiles to α,β-unsaturated aryl esters.

Chang Shu, Honglei Liu, Alexandra M Z Slawin, Cameron Carpenter-Warren, Andrew D Smith

Abstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Determination of the pEuropean journal of organic chemistry · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Enantioselective Michael-Proton Transfer-Lactamization for Pyroglutamic Acid Derivatives: Synthesis of Dimethyl-(Organic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chang ShuEaStCHEM, School of Chemistry, University of St Andrews North Haugh, St Andrews Fife KY16 9ST UK ads10@st-andrews.ac.uk.
Honglei LiuEaStCHEM, School of Chemistry, University of St Andrews North Haugh, St Andrews Fife KY16 9ST UK ads10@st-andrews.ac.uk.
Alexandra M Z SlawinEaStCHEM, School of Chemistry, University of St Andrews North Haugh, St Andrews Fife KY16 9ST UK ads10@st-andrews.ac.uk.ORCID https://orcid.org/0000-0002-9527-6418
Cameron Carpenter-WarrenEaStCHEM, School of Chemistry, University of St Andrews North Haugh, St Andrews Fife KY16 9ST UK ads10@st-andrews.ac.uk.
Andrew D SmithEaStCHEM, School of Chemistry, University of St Andrews North Haugh, St Andrews Fife KY16 9ST UK ads10@st-andrews.ac.uk.ORCID https://orcid.org/0000-0002-2104-7313

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The isothiourea-catalysed enantioselective Michael addition of 3-aryloxindole and 4-substituted-dihydropyrazol-3-one pronucleophiles to α,β-unsaturated

Identifiers

PMID34040717
PMCPMC8133005

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.