Evidence map›Paper›PMID 34040713›Full record

ArticleChemical science2019

High frequency, calibration-free molecular measurements

Hui Li, Shaoguang Li, Jun Dai, Chengcheng Li, Man Zhu, Hongxing Li, Xiaoding Lou, Fan Xia, Kevin W Plaxco

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 79 citations in OpenAlex.

  1. Review
  2. Continuous, Week-Long, Seconds-ResolvedJournal of the American Chemical Society · 2026
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  14. Long-TermbioRxiv : the preprint server for biology · 2023
    Article
  15. Review
  16. Clinical Evaluation of a Novel Insulin Immunosensor.Journal of diabetes science and technology · 2023
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Hui LiEngineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences Wuhan 430074 China xiafan@cug.edu.cn.ORCID https://orcid.org/0000-0001-7849-9735
Shaoguang LiEngineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences Wuhan 430074 China xiafan@cug.edu.cn.ORCID https://orcid.org/0000-0001-6101-0358
Jun DaiDepartment of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430074 China.ORCID https://orcid.org/0000-0002-2837-1976
Chengcheng LiEngineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences Wuhan 430074 China xiafan@cug.edu.cn.ORCID https://orcid.org/0000-0002-4843-5404
Man ZhuEngineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences Wuhan 430074 China xiafan@cug.edu.cn.ORCID https://orcid.org/0000-0003-4136-222X
Hongxing LiEngineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences Wuhan 430074 China xiafan@cug.edu.cn.ORCID https://orcid.org/0000-0001-7674-6392
Xiaoding LouEngineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences Wuhan 430074 China xiafan@cug.edu.cn.ORCID https://orcid.org/0000-0002-6556-2034
Fan XiaEngineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences Wuhan 430074 China xiafan@cug.edu.cn.ORCID https://orcid.org/0000-0001-7705-4638
Kevin W PlaxcoDepartment of Chemistry and Biochemistry, University of California Santa Barbara Santa Barbara California 93106 USA kwp@chem.ucsb.edu.ORCID https://orcid.org/0000-0003-4772-8771
China University of Geosciences · CNSanta Barbara City College · USTongji Hospital · CN

Funding

Bio-electrochemical detectors for in vivo continuous monitoringR01EB022015 · NIBIB · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI KIPPIN, TOD EDWARD, PLAXCO, KEVIN W · 2017 to 2025
$4.6M
NIBIB NIH HHS R01 EB022015
6 · The paper itself

Abstract

Abolition of the need for end-users to perform sensor calibration proved key to the widespread use of home-glucose monitors. Motivated by this observation here we have adapted electrochemical aptamer-based (E-AB) sensors, a sensing technology that is far more general than the glucose monitor, to the problem of performing calibration-free

Identifiers

PMID34040713
PMCPMC8132996
OpenAlexW2984104714

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.