Evidence map›Paper›PMID 34040603›Full record

ArticleFrontiers in immunology2021

Marginal Zone B Cells Assist With Neutrophil Accumulation to Fight Against Systemic

Li-Wen Lo, Chia-Wei Chang, Ming-Feng Chiang, I-Ying Lin, Kuo-I Lin

Abstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Role of Neutrophils on the Ocular Surface.International journal of molecular sciences · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Pathogens (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Review
  8. Destabilisation of T cell-dependent humoral immunity in sepsis.Clinical science (London, England : 1979) · 2024
    Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Li-Wen LoGraduate Institute of Immunology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chia-Wei ChangGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Ming-Feng ChiangGenomics Research Center, Academia Sinica, Taipei, Taiwan.
I-Ying LinGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Kuo-I LinGraduate Institute of Immunology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In addition to regulating immune responses by producing antibodies that confer humoral immunity, B cells can also affect these responses by producing cytokines. How B cells participate in the clearance of pathogenic infections

Indexed as

AnimalsBacteremiaB-LymphocytesCell DifferentiationCells, CulturedChemokine CXCL1Chemokine CXCL2Immune System DiseasesImmunity, CellularInterleukin-6Leukocyte DisordersLymphocyte ActivationMiceMice, KnockoutNeutrophilsPeptidoglycanChemokine CXCL1Chemokine CXCL2Interleukin-6PeptidoglycanFRETIL-6marginal zone B cellneutrophilStaphylococcus aureus

Identifiers

PMID34040603
PMCPMC8141640

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.