Evidence map›Paper›PMID 34040586›Full record

ArticleFrontiers in endocrinology2021

Optimising Follicular Development, Pituitary Suppression, Triggering and Luteal Phase Support During Assisted Reproductive Technology: A Delphi Consensus.

Raoul Orvieto, Christos A Venetis, Human M Fatemi, Thomas D'Hooghe, Robert Fischer, Yulia Koloda, Marcos Horton, Michael Grynberg, Salvatore Longobardi, Sandro C Esteves and 3 more

Open access · goldAbstract readConsensus Statement
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Influencing factors of fertilization failure duringFrontiers in endocrinology · 2026
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  17. Progesterone in Pregnancy: Evidence-Based Strategies to Reduce Miscarriage and Enhance Assisted Reproductive Technology.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 13 countries.

Raoul OrvietoInfertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center (Tel Hashomer), Ramat Gan, Israel.
Christos A VenetisCentre for Big Data Research in Health & School of Women's and Children's Health, UNSW Medicine, University of New South Wales, Sydney, NSW, Australia.
Human M FatemiAssisted Reproductive Technology (ART), Fertility Clinics, Abu Dhabi, United Arab Emirates.
Thomas D'HoogheGlobal Medical Affairs, Research and Development, Merck Healthcare KGaA, Darmstadt, Germany.
Robert FischerIVF Unit, Fertility Center Hamburg, Hamburg, Germany.
Yulia KolodaCenter of Reproduction "Life Line", Moscow, Russia.
Marcos HortonPregna Medicina Reproductiva, Buenos Aires, Argentina.
Michael GrynbergService de Médecine de la Reproduction et Préservation de la Fertilité, Hôpital Antoine Béclère, Clamart, France.
Salvatore LongobardiGlobal Clinical Development, Merck Serono, Italy, an Affiliate of Merck KGaA, Darmstadt, Germany.
Sandro C EstevesANDROFERT, Andrology and Human Reproduction Clinic, Center for Male Reproduction, Campinas, Brazil.
Sesh K SunkaraFaculty of Life Sciences and Medicine, King's College London, London, United Kingdom.
Yuan LiMedical Center for Human Reproduction, Beijing Chao-yang Hospital, Capital Medical University, Beijing, China.
Carlo AlviggiDepartment of Neuroscience, Reproductive Science and Odontostomatology, University of Naples Federico II, Naples, Italy.
Aarhus University · DKBeijing Chao-Yang Hospital · CNHôpital Antoine-Béclère · FRHospitals Contribution Fund (Australia) · AUIVI Middle East Fertility Clinic · AEKing's College London · GBMerck (Germany) · DEMerck Serono (Italy) · ITRussian Medical Academy of Continuous Professional Education · RUTel Aviv University · ILUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A Delphi consensus was conducted to evaluate global expert opinions on key aspects of assisted reproductive technology (ART) treatment. Methods: Ten experts plus the Scientific Coordinator discussed and amended statements plus supporting references proposed by the Scientific Coordinator. The statements were distributed Results: Eighteen statements were developed. All statements reached consensus and the most relevant are summarised here. Conclusions: This Delphi consensus provides a real-world clinical perspective on the specific approaches during the key steps of ART treatment from a diverse group of international experts. Additional guidance from clinicians on ART strategies could complement guidelines and policies, and may help to further improve treatment outcomes.

Indexed as

OogenesisChorionic GonadotropinDelphi TechniqueFemaleFertilization in VitroFollicle Stimulating Hormone, HumanGonadotropin-Releasing HormoneHumansLuteal PhaseOocytesOvulation InductionPituitary GlandPractice Guidelines as TopicPregnancyProgesteroneReproductive Techniques, AssistedChorionic GonadotropinFollicle Stimulating Hormone, HumanGonadotropin-Releasing HormoneProgesteroneassisted reproductive technology (ART)expert opiniongonadotropinsluteal phase supportoocyte maturationoptimisationovarian stimulationtrigger

Identifiers

PMID34040586
PMCPMC8142593
OpenAlexW3161869945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.