ReviewNature reviews. Neurology2021
The childhood migraine syndrome.
Review in Nature reviews. Neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 36 citations in OpenAlex.
- Migraine in children and adolescents.Developmental medicine and child neurology · 2026Review
- Clinical Differentiation of Self-Limited Epilepsy With Autonomic Seizures (Panayiotopoulos Syndrome) and Childhood Migraine.Neurology. Clinical practice · 2026Article
- Allergic diseases in early childhood and their association with migraine: a large-scale retrospective study.Frontiers in allergy · 2026Article
- Headache symptoms in children and adolescents with ADHD: evaluating family history and the role of methylphenidate treatment.Acta neurologica Belgica · 2025Article
- Current Trends in Pediatric Migraine: Clinical Insights and Therapeutic Strategies.Brain sciences · 2025Review
- Evidence-based review and frontiers of migraine therapy.Neurogastroenterology and motility · 2025Review
- Rising global burden of migraine among adolescents and young adults: a 30-year analysis (1990-2021).Frontiers in neurology · 2025Article
- Calcitonin-Gene-Related Peptide in Migraine and Tension-Type Headache in Children During Interictal Period.Diagnostics (Basel, Switzerland) · 2024Article
- From the New Diagnostic Criteria to COVID-19 Pandemic Passing Through the Placebo Effect. What Have We Learned in the Management of Pediatric Migrane Over the Past 5 Years?Frontiers in neurology · 2022Review
- How to Assess the Headache-Sleep Disorders Comorbidity in Children and Adolescents.Journal of clinical medicine · 2021Review
- Migraine and Its Equivalents: What Do They Share? A Narrative Review on Common Pathophysiological Patterns.Life (Basel, Switzerland) · 2021Review
- Sleep Disorders in Pediatric Migraine: A Questionnaire-Based Study.Journal of clinical medicine · 2021Article
- Outcomes of Migraine and Tension-Type Headache in Children and Adolescents.Life (Basel, Switzerland) · 2021Article
- Short-duration migraine without aura in children: a retrospective cohort study of attack duration and prognosis.Frontiers in neurologyArticle
- Restless legs syndrome and growing pains in childhood: understanding the link.Frontiers in neurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Migraine is a complex genetic brain disorder with an intricate pathogenesis and polymorphous clinical presentations, particularly in children. In this Perspective, we describe the different phenotypes of migraine in children, including conditions that have been referred to in the International Classification of Headache Disorders as "syndromes that may be related to migraine''. Evidence is presented for the integration of abdominal migraine, cyclical vomiting syndrome, benign paroxysmal vertigo, benign paroxysmal torticollis and infantile colic into the unified diagnosis of 'childhood migraine syndrome' on the basis of clinical and epidemiological characteristics, and shared inheritance. In our opinion, such integration will guide clinicians from specialities other than neurology to consider migraine in the assessment of children with these disorders, as well as stimulate research into the genetics, pathophysiology and clinical features of all disorders within the syndrome. A diagnosis of childhood migraine syndrome would also enable patients to benefit from inclusion in clinical trials of old and new migraine treatments, thus potentially increasing the number of treatment options available.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.