Evidence map›Paper›PMID 34040075›Full record

ArticleScientific reports2021

Wada test results contribute to the prediction of change in verbal learning and verbal memory function after temporal lobe epilepsy surgery.

Nadine Conradi, Friederike Rosenberg, Susanne Knake, Louise Biermann, Anja Haag, Iris Gorny, Anke Hermsen, Viola von Podewils, Marion Behrens, Marianna Gurschi and 8 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Nadine ConradiDepartment of Neurology, Epilepsy Center Frankfurt Rhine-Main, University Hospital Frankfurt and Goethe University, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany. Nadine.Conradi@kgu.de.
Friederike RosenbergDepartment of Neurology, Epilepsy Center Frankfurt Rhine-Main, University Hospital Frankfurt and Goethe University, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.
Susanne KnakeLOEWE Center for Personalized Translational Epilepsy Research (CePTER), Goethe University, Frankfurt am Main, Germany.
Louise BiermannDepartment of Neurology, Epilepsy Center Hessen, Philipps-University Marburg, Marburg, Germany.
Anja HaagDepartment of Neurology, Epilepsy Center Hessen, Philipps-University Marburg, Marburg, Germany.
Iris GornyDepartment of Neurology, Epilepsy Center Hessen, Philipps-University Marburg, Marburg, Germany.
Anke HermsenDepartment of Neurology, Epilepsy Center Frankfurt Rhine-Main, University Hospital Frankfurt and Goethe University, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.
Viola von PodewilsDepartment of Neurology, University Medicine Greifswald, Greifswald, Germany.
Marion BehrensDepartment of Neurology, University Hospital Frankfurt and Goethe University, Frankfurt am Main, Germany.
Marianna GurschiDepartment of Neuroradiology, Philipps-University Marburg, Marburg, Germany.
Richard du Mesnil de RochemontInstitute of Neuroradiology, University Hospital Frankfurt and Goethe University, Frankfurt am Main, Germany.
Katja MenzlerDepartment of Neurology, Epilepsy Center Hessen, Philipps-University Marburg, Marburg, Germany.
Sebastian BauerDepartment of Neurology, Epilepsy Center Frankfurt Rhine-Main, University Hospital Frankfurt and Goethe University, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.
Susanne Schubert-BastDepartment of Neurology, Epilepsy Center Frankfurt Rhine-Main, University Hospital Frankfurt and Goethe University, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.
Christopher NimskyDepartment of Neurosurgery, Philipps-University Marburg, Marburg, Germany.
Jürgen KonczallaDepartment of Neurosurgery, University Hospital Frankfurt and Goethe University, Frankfurt am Main, Germany.
Felix RosenowDepartment of Neurology, Epilepsy Center Frankfurt Rhine-Main, University Hospital Frankfurt and Goethe University, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.
Adam StrzelczykDepartment of Neurology, Epilepsy Center Frankfurt Rhine-Main, University Hospital Frankfurt and Goethe University, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the clinical usefulness of the Wada test (WT) has been debated among researchers in the field. Therefore, we aimed to assess its contribution to the prediction of change in verbal learning and verbal memory function after epilepsy surgery. Data from 56 patients with temporal lobe epilepsy who underwent WT and subsequent surgery were analyzed retrospectively. Additionally, a standard neuropsychological assessment evaluating attentional, learning and memory, visuospatial, language, and executive function was performed both before and 12 months after surgery. Hierarchical linear regression analyses were used to determine the incremental value of WT results over socio-demographic, clinical, and neuropsychological characteristics in predicting postsurgical change in patients' verbal learning and verbal memory function. The incorporation of WT results significantly improved the prediction models of postsurgical change in verbal learning (∆R

Indexed as

Epilepsy, Temporal LobeMemoryNeuropsychological TestsVerbal LearningAdultFemaleHumansMaleMiddle AgedRetrospective StudiesYoung Adult

Identifiers

PMID34040075
PMCPMC8154896

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