Evidence map›Paper›PMID 34040032›Full record

ArticleScientific reports2021

Visualization of elastin using cardiac magnetic resonance imaging after myocardial infarction as inflammatory response.

Britta Elkenhans, Andrea Protti, Ajay Shah, David Onthank, René Botnar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Molecular contrast agents for post-infarct cardiac remodelling: a contemporary review.European heart journal. Imaging methods and practice · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Multinuclear MRI in Drug Discovery.Molecules (Basel, Switzerland) · 2022
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Britta ElkenhansDepartment of Cardiology, Pneumology, and Angiology, University Hospital Aachen, Heinrich Heine University Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany. britta@elkenhans.de.
Andrea ProttiHarvard Medical School, Department of Imaging, Lurie Family Imaging Center, Boston, USA.
Ajay ShahCardiovascular Division, King's College London, London, UK.
David OnthankLantheus Medical Imaging, North Billerica, USA.
René BotnarCardiovascular Division, King's College London, London, UK.
King's College London · GBDüsseldorf University Hospital · DEImaging Center · USLantheus Medical Imaging (United States) · US

Funding

British Heart Foundation CH/1999001/11735
6 · The paper itself

Abstract

The aim of this study was to investigate the merits of magnetic resonance imaging (MRI) using an elastin-binding contrast agent after myocardial infarction in mouse models with deletions of monocyte populations. Permanent ligation of the left anterior descending (LAD) artery was conducted in 10 wild-type mice and 10 each of three knockout models: CX3CR

Indexed as

ElastinMagnetic Resonance ImagingMice, KnockoutMyocardial InfarctionReceptors, CCR2AnimalsChemokine CCL2Contrast MediaCX3C Chemokine Receptor 1Disease Models, AnimalInflammationMaleMiceMice, Inbred C57BLCcl2 protein, mouseCcr2 protein, mouseChemokine CCL2Contrast MediaCX3C Chemokine Receptor 1Cx3cr1 protein, mouseElastinReceptors, CCR2

Identifiers

PMID34040032
PMCPMC8155029
OpenAlexW3163955373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.