Evidence map›Paper›PMID 34040006›Full record

ArticleScientific reports2021

Prenatal exposures to mixtures of endocrine disrupting chemicals and children's weight trajectory up to age 5.5 in the SELMA study.

Katherine Svensson, Eva Tanner, Chris Gennings, Christian Lindh, Hannu Kiviranta, Sverre Wikström, Carl-Gustaf Bornehag

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Katherine SvenssonDepartment of Health Sciences, Karlstad University, Universitetsgatan 2, 651 88, Karlstad, Sweden.
Eva TannerDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Chris GenningsDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Christian LindhDivision of Occupational and Environmental Medicine, Lund University, Lund, Sweden.
Hannu KivirantaEnvironmental Health Unit, Finnish Institute for Health and Welfare, Kuopio, Finland.
Sverre WikströmSchool of Medical Sciences, Örebro University, Örebro, Sweden.
Carl-Gustaf BornehagDepartment of Health Sciences, Karlstad University, Universitetsgatan 2, 651 88, Karlstad, Sweden. carl-gustaf.bornehag@kau.se.
Icahn School of Medicine at Mount Sinai · USFinnish Institute for Health and Welfare · FIKarlstad University · SELund University · SEÖrebro University · SE

Funding

Methods for Data Integration and Risk Assessment for Environmental MixturesR01ES028811 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI COULL, BRENT ANDREW, GENNINGS, CHRIS · 2018 to 2021
$1.9M
NIEHS NIH HHS R01 ES028811Powering Research Through Innovative Methods for Mixtures in Epidemiology (PRIME) R01ES028811-01
6 · The paper itself

Abstract

Exposure to endocrine disrupting chemicals (EDCs) may impact early growth, although information is limited on exposure to combination of multiple EDCs. We aimed to evaluate the effect of prenatal exposure to EDC mixtures on birthweight z-scores and childhood weight trajectories. Twenty-six proven and suspected EDCs, were analyzed in prenatal urine and blood samples from 1118 mothers participating in the Swedish Environmental Longitudinal Mother and child Asthma and allergy (SELMA) study. Two growth parameters were estimated from each child's weight trajectory from birth to 5.5 years of age: infant growth spurt rate and age at infant peak growth velocity (PGV). Weighted quantile sum (WQS) regression was used to estimate the mixture effect and identify chemicals of concern. A one-unit increase in the EDC mixture WQS index, was associated with decreased birthweight z-scores of 0.11 (95% CI - 0.16, - 0.06), slower infant growth spurt rate of 0.01 (95% CI - 0.03, - 0.01, on the log

Indexed as

Birth WeightEndocrine DisruptorsPrenatal Exposure Delayed EffectsAdultBody WeightChild DevelopmentChild, PreschoolEnvironmental PollutantsFemaleHumansInfantInfant, NewbornLongitudinal StudiesMaleMaternal ExposurePregnancyEndocrine DisruptorsEnvironmental Pollutants

Identifiers

PMID34040006
PMCPMC8155069
OpenAlexW3165866464

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.