Evidence map›Paper›PMID 34039713›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Differing biophysical properties underpin the unique signaling potentials within the plant phytochrome photoreceptor families.

E Sethe Burgie, Zira T K Gannam, Katrice E McLoughlin, Christopher D Sherman, Alex S Holehouse, Robert J Stankey, Richard D Vierstra

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 50 citations in OpenAlex.

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  6. Preparation of Phycocyanobilin (PCB) with and withoutMethods in molecular biology (Clifton, N.J.) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

E Sethe BurgieDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130.ORCID 0000-0002-6520-9126
Zira T K GannamDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130.ORCID 0000-0002-9680-4067
Katrice E McLoughlinDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130.
Christopher D ShermanDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130.
Alex S HolehouseDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-4155-5729
Robert J StankeyDepartment of Genetics, University of Wisconsin, Madison, WI 53706.ORCID 0000-0003-1259-2296
Richard D VierstraDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130; rdvierstra@wustl.edu.ORCID 0000-0003-0210-3516
Washington University in St. Louis · USUniversity of Wisconsin–Madison · US

Funding

Phytochromes: Structural Perspectives on Photoactivation and SignalingR01GM127892 · NIGMS · WASHINGTON UNIVERSITY · PI JEZ, JOSEPH MARTIN · 2018 to 2025
$2.5M
NIGMS NIH HHS R01 GM127892
6 · The paper itself

Abstract

Many aspects of photoperception by plants and microorganisms are initiated by the phytochrome (Phy) family of photoreceptors that detect light through interconversion between red light- (Pr) and far-red light-absorbing (Pfr) states. Plants synthesize a small family of Phy isoforms (PhyA to PhyE) that collectively regulate photomorphogenesis and temperature perception through redundant and unique actions. While the selective roles of these isoforms have been partially attributed to their differing abundances, expression patterns, affinities for downstream partners, and turnover rates, we show here from analysis of recombinant

Indexed as

Light Signal TransductionArabidopsisEscherichia coliPhytochromeProtein IsoformsRecombinant ProteinsThermosensingPhytochromeProtein IsoformsRecombinant Proteinsphotochemistryphotoreceptorphytochrometemperature sensingthermal reversion

Identifiers

PMID34039713
PMCPMC8179155
OpenAlexW3164762765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.