Evidence map›Paper›PMID 34039711›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Oviductal motile cilia are essential for oocyte pickup but dispensable for sperm and embryo transport.

Shuiqiao Yuan, Zhuqing Wang, Hongying Peng, Sean M Ward, Grant W Hennig, Huili Zheng, Wei Yan

Open access · bronzeAbstract readVideo-Audio Media
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 105 citations in OpenAlex.

  1. Successful oocyte transport through the oviduct does not depend on the longitudinal alignment of oviduct epithelial folds.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  11. Exome sequencing-based identification ofFrontiers in molecular biosciences · 2026
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Shuiqiao YuanDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV 89557; shuiqiaoyuan@hust.edu.cn wei.yan@lundquist.org.ORCID 0000-0003-1460-7682
Zhuqing WangDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV 89557.ORCID 0000-0002-3988-0733
Hongying PengDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV 89557.
Sean M WardDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV 89557.
Grant W HennigDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV 89557.
Huili ZhengDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV 89557.
Wei YanDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV 89557; shuiqiaoyuan@hust.edu.cn wei.yan@lundquist.org.ORCID 0000-0001-9569-9026
University of Nevada, Reno · US

Funding

Mechanism Underlying the Transduction of Epimutations from the Soma to the Male GermlineP50HD098593 · NICHD · UNIVERSITY OF NEVADA RENO · PI ZHOU, TONG · 2019 to 2024
$7.2M
Single Cell Molecular ExpressionP30GM110767 · NIGMS · UNIVERSITY OF NEVADA RENO · PI SANDERS, KENTON M · 2014 to 2018
$5.4M
Epitranscriptomic regulation of spermatogenesis and male fertilityR01HD099924 · NICHD · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI YAN, WEI · 2020 to 2024
$1.9M
Messenger RNA Fate Control in SpermatogenesisR01HD085506 · NICHD · UNIVERSITY OF NEVADA RENO · PI SANDERS, KENTON M · 2015 to 2019
$1.5M
Are sperm-borne small RNAs important?R21HD071736 · NICHD · UNIVERSITY OF NEVADA RENO · PI YAN, WEI · 2012 to 2013
$380k
Small RNA profiling during spermatogenesisR03HD048855 · NICHD · UNIVERSITY OF NEVADA RENO · PI YAN, WEI · 2005 to 2006
$143k
NICHD NIH HHS P50 HD098593NICHD NIH HHS R01 HD085506NICHD NIH HHS R01 HD099924NICHD NIH HHS R03 HD048855NICHD NIH HHS R21 HD071736NIGMS NIH HHS P30 GM110767
6 · The paper itself

Abstract

Mammalian oviducts play an essential role in female fertility by picking up ovulated oocytes and transporting and nurturing gametes (sperm/oocytes) and early embryos. However, the relative contributions to these functions from various cell types within the oviduct remain controversial. The oviduct in mice deficient in two microRNA (miRNA) clusters (

Indexed as

FertilityOvulationAnimalsBlastocystCiliaEmbryo ImplantationFemaleMaleMiceMice, KnockoutMicroRNAsMovementOocytesOviductsSpermatozoaMicroRNAsMIRN34a microRNA, mouseMirn449 microRNA, mouseciliopathyFallopian tubefertilitymicroRNAsmulticiliogenesis

Identifiers

PMID34039711
PMCPMC8179221
OpenAlexW3165209611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.