Evidence map›Paper›PMID 34039635›Full record

ArticleCancer research2021

Spectral Endoscopy Enhances Contrast for Neoplasia in Surveillance of Barrett's Esophagus.

Dale J Waterhouse, Wladyslaw Januszewicz, Sharib Ali, Rebecca C Fitzgerald, Massimiliano di Pietro, Sarah E Bohndiek

Open access · hybridAbstract read
In one paragraph

Article in Cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Dale J WaterhouseDepartment of Physics and Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0001-5530-6857
Wladyslaw JanuszewiczDepartment of Gastroenterology, Hepatology, and Clinical Oncology, Medical Center for Postgraduate Education, Warsaw, Poland.
Sharib AliInstitute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom.ORCID 0000-0003-1313-3542
Rebecca C FitzgeraldMRC Cancer Unit, Hutchison/MRC Research Center, University of Cambridge, Cambridge, United Kingdom.
Massimiliano di PietroMRC Cancer Unit, Hutchison/MRC Research Center, University of Cambridge, Cambridge, United Kingdom. seb53@cam.ac.uk md460@mrc-cu.cam.ac.uk.
Sarah E BohndiekDepartment of Physics and Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom. seb53@cam.ac.uk md460@mrc-cu.cam.ac.uk.ORCID 0000-0003-0371-8635
Cancer Research UK Cambridge Center · GBHutchison/MRC Research Centre · GBPostgraduate School of Molecular Medicine · PLUniversity of Oxford · GB

Funding

Cancer Research UK 16267Cancer Research UK 16465Cancer Research UK 21102Cancer Research UK 24669Cancer Research UK A16267Cancer Research UK A21102Cancer Research UK A24669Cancer Research UK C14303/A17197Cancer Research UK C47594/A21102Cancer Research UK C9545/A29580
6 · The paper itself

Abstract

Early detection of esophageal neoplasia enables curative endoscopic therapy, but the current diagnostic standard of care has low sensitivity because early neoplasia is often inconspicuous with conventional white-light endoscopy. Here, we hypothesized that spectral endoscopy could enhance contrast for neoplasia in surveillance of patients with Barrett's esophagus. A custom spectral endoscope was deployed in a pilot clinical study of 20 patients to capture 715

Indexed as

AlgorithmsAdenocarcinomaAdolescentAdultAgedAged, 80 and overBarrett EsophagusCase-Control StudiesEndoscopyEsophageal NeoplasmsFemaleFollow-Up StudiesHumansMaleMiddle AgedPilot Projects

Identifiers

PMID34039635
PMCPMC7611389
OpenAlexW3165139116

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.