ArticleScience advances2021
A hindbrain dopaminergic neural circuit prevents weight gain by reinforcing food satiation.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Beyond Pleasure: Unraveling the Multifaceted Role of Dopamine in Obesity and Metabolic Regulation.Current obesity reports · 2026Review
- Reduced melanocortin tone modulates feeding during pregnancy in mice.Nature communications · 2026Article
- Dopamine Boosts Motivation for Prosocial Effort in Parkinson's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- A Drd1-cre mouse line with nucleus accumbens gene dysregulation exhibits blunted fentanyl seeking.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Complexity of the Hypothalamic Oxytocin System and its Involvement in Brain Functions and Diseases.Neuroscience bulletin · 2025Review
- Dopaminergic neurons in the paraventricular hypothalamus extend the food consumption phase.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Replacing rice straw with peanut vine andAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- A vagus nerve dominant tetra-synaptic ascending pathway for gastric pain processing.Nature communications · 2024Article
- Probing the molecular and cellular pathological mechanisms of schizophrenia using human induced pluripotent stem cell models.Schizophrenia research · 2024Review
- Modulation of mechanosensation by endogenous dopaminergic signaling in the lateral parabrachial nucleus in mice.Pain reports · 2024Article
- Morphological Tracing and Functional Identification of Monosynaptic Connections in the Brain: A Comprehensive Guide.Neuroscience bulletin · 2024Review
- Transient cAMP production drives rapid and sustained spiking in brainstem parabrachial neurons to suppress feeding.Neuron · 2024Article
- Association between personality traits, eating behaviors, and the genetic polymorphismsFrontiers in genetics · 2024Article
- Identification of a GABAergic neural circuit governing leptin signaling deficiency-induced obesity.eLife · 2023Article
- D1 receptor-expressing neurons in ventral tegmental area alleviate mouse anxiety-like behaviors via glutamatergic projection to lateral septum.Molecular psychiatry · 2023Article
- Effect of stimulants on final adult height.Journal of pediatric endocrinology & metabolism : JPEM · 2022Review
- Molecular and anatomical characterization of parabrachial neurons and their axonal projections.eLife · 2022Article
- A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice.Nature neuroscience · 2022Article
- Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding.Nature communications · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
The neural circuitry mechanism that underlies dopaminergic (DA) control of innate feeding behavior is largely uncharacterized. Here, we identified a subpopulation of DA neurons situated in the caudal ventral tegmental area (cVTA) directly innervating DRD1-expressing neurons within the lateral parabrachial nucleus (LPBN). This neural circuit potently suppresses food intake via enhanced satiation response. Notably, this cohort of DA
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.