ArticleMicrobiome2021
Characterization of the public transit air microbiome and resistome reveals geographical specificity.
Article in Microbiome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Residential proximity to intensive animal agriculture associates with increased prevalence of antimicrobial resistance in homes.Journal of exposure science & environmental epidemiology · 2026Article
- Recent Microbial Evolutionary Insights From Metagenomics.Genome biology and evolution · 2026Review
- Travel microbiota: a novel frontier in travel medicine exploring microbial shifts across transportation modes.Tropical diseases, travel medicine and vaccines · 2026Review
- Spatial and temporal patterns of public transit aerobiomes.Microbiome · 2026Article
- Dynamic airborne mycobiome in the metropolitan city transit system is driven by seasonality and station type.Microbiology spectrum · 2025Article
- Global biogeography of airborne viruses in public transit systems and their host interactions.Microbiome · 2025Article
- Article
- Detection of the ST111 Global High-RiskCurrent issues in molecular biology · 2025Article
- Citywide metagenomic surveillance of food centres reveals local microbial signatures and antibiotic resistance gene enrichment.npj antimicrobials and resistance · 2025Article
- First Animal Source Metagenome Assembly ofPathogens (Basel, Switzerland) · 2025Article
- From air to insight: the evolution of airborne DNA sequencing technologies.Microbiology (Reading, England) · 2025Review
- Analysis of metagenomic data.Nature reviews. Methods primers · 2025Article
- Parents-child multiple sites of microbial and metabolic signatures in autism spectrum disorder.Frontiers in microbiology · 2025Article
- The indoors microbiome and human health.Nature reviews. Microbiology · 2024Review
- Microbiome Geographic Population Structure (mGPS) Detects Fine-Scale Geography.Genome biology and evolution · 2024Article
- Diverse and specialized metabolic capabilities of microbes in oligotrophic built environments.Microbiome · 2024Article
- Sampling efficiency and nucleic acid stability during long-term sampling with different bioaerosol samplers.Environmental monitoring and assessment · 2024Article
- Biocontrol in built environments to reduce pathogen exposure and infection risk.The ISME journal · 2024Review
- Exploring the role of indoor microbiome and environmental characteristics in rhinitis symptoms among university students.Frontiers in microbiomes · 2024Article
- Who inhabits the built environment? A microbiological point of view on the principal bacteria colonizing our urban areas.Frontiers in microbiology · 2024Review
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Authors and funding
19 authors.
Funding
Abstract
backgroundThe public transit is a built environment with high occupant density across the globe, and identifying factors shaping public transit air microbiomes will help design strategies to minimize the transmission of pathogens. However, the majority of microbiome works dedicated to the public transit air are limited to amplicon sequencing, and our knowledge regarding the functional potentials and the repertoire of resistance genes (i.e. resistome) is limited. Furthermore, current air microbiome investigations on public transit systems are focused on single cities, and a multi-city assessment of the public transit air microbiome will allow a greater understanding of whether and how broad environmental, building, and anthropogenic factors shape the public transit air microbiome in an international scale. Therefore, in this study, the public transit air microbiomes and resistomes of six cities across three continents (Denver, Hong Kong, London, New York City, Oslo, Stockholm) were characterized.
resultsCity was the sole factor associated with public transit air microbiome differences, with diverse taxa identified as drivers for geography-associated functional potentials, concomitant with geographical differences in species- and strain-level inferred growth profiles. Related bacterial strains differed among cities in genes encoding resistance, transposase, and other functions. Sourcetracking estimated that human skin, soil, and wastewater were major presumptive resistome sources of public transit air, and adjacent public transit surfaces may also be considered presumptive sources. Large proportions of detected resistance genes were co-located with mobile genetic elements including plasmids. Biosynthetic gene clusters and city-unique coding sequences were found in the metagenome-assembled genomes.
conclusionsOverall, geographical specificity transcends multiple aspects of the public transit air microbiome, and future efforts on a global scale are warranted to increase our understanding of factors shaping the microbiome of this unique built environment.
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