ReviewJournal of eating disorders2021
Adapting a neuroscience-informed intervention to alter reward mechanisms of anorexia nervosa: a novel direction for future research.
Review in Journal of eating disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- A randomized, controlled pilot study of positive affect treatment adapted for anorexia nervosa.The International journal of eating disorders · 2024Trial
- Correcting the reward imbalance in binge eating: A pilot randomized trial of reward re-training treatment.Appetite · 2022Trial
- A neurodevelopmental model of eating disorder risk in midlife to older adulthood.Neuroscience and biobehavioral reviews · 2026Review
- Gamified Assessment of Cognitive Impulsivity in Eating Disorders and Mental Ill-Health: Mixed Methods Study Incorporating Lived Experience Co-Design and Evaluation.JMIR serious games · 2026Article
- Expanding the Scope of Open Weighing to Target Anxiety About the Consequences of Weight Gain in Cognitive-Behavioral Therapy for Eating Disorders.The International journal of eating disorders · 2026Article
- Feeling Better Before, Not After: An Ecological Momentary Assessment of Affect Around Exercise in Women with Eating Disorders.medRxiv : the preprint server for health sciences · 2025Article
- Investigating Associations Between General and Disorder-Specific Reward and Suicidality in Anorexia Nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2025Article
- Meal plan inclusions and exclusions in the inpatient, outpatient and community setting for adolescent and adult eating disorder care: a scoping review.Journal of eating disorders · 2025Review
- Informed consent competency assessment for brain-computer interface clinical research and application in psychiatric disorders: A systematic review.World journal of psychiatry · 2025Article
- Identification of Affective- and Social-Reinforcement Functions of Driven Exercise: Evidence From Three Samples.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- The current clinical approach to feeding and eating disorders aimed to increase personalization of management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- Anticipatory and Consummatory Responses Across Reward Domains in Adolescents With Anorexia Nervosa.The International journal of eating disorders · 2024Article
- Reward responsivity and habit formation in the co-occurrence of restrictive eating and nonsuicidal self-injury.Journal of psychiatric research · 2024Article
- Reducing Relapse by Enhancing Reward Responsivity in Anorexia Nervosa: The VIBRANT (Virtual Interventions for Bolstering Recovery following Anorexia Nervosa Treatment) TrialJournal of psychiatry and brain science · 2024Article
- Anticipatory and consummatory pleasure in avoidant/restrictive food intake disorder.Journal of eating disorders · 2023Article
- Difficulties with positive emotion regulation in anorexia nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2023Article
- Aberrant reward-related neural activation: Dimensional correlate of binge-eating severity or categorical marker of binge eating?Journal of psychiatric research · 2023Article
- Learned industriousness as a translational mechanism in anorexia nervosa.Nature reviews psychology · 2023Article
- Positive affect dysregulation and its relation to binge eating size and frequency.Frontiers in psychology · 2023Article
- Is decision-making impairment an endophenotype of anorexia nervosa?European psychiatry : the journal of the Association of European Psychiatrists · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Accumulating psychobiological data implicate reward disturbances in the persistence of anorexia nervosa (AN). Evidence suggests that individuals with AN demonstrate decision-making deficits similar to those with mood and anxiety disorders that cause them to under-respond to many conventionally rewarding experiences (e.g., eating, interacting socially). In contrast, unlike individuals with other psychiatric disorders, individuals with AN simultaneously over-respond to rewards associated with eating-disorder behaviors (e.g., restrictive eating, exercising). This pattern of reward processing likely perpetuates eating-disorder symptoms, as the rewards derived from eating-disorder behaviors provide temporary relief from the anhedonia associated with limited responsivity to other rewards. Positive Affect Treatment (PAT) is a cognitive-behavioral intervention designed to target reward deficits that contribute to anhedonia in mood and anxiety disorders, including problems with reward anticipation, experiencing, and learning. PAT has been found to promote reward responsivity and clinical improvement in mood and anxiety disorders. This manuscript will: (1) present empirical evidence supporting the promise of PAT as an intervention for AN; (2) highlight nuances in the maintaining processes of AN that necessitate adaptations of PAT for this population; and (3) suggest future directions in research on PAT and other reward-based treatments that aim to enhance clinical outcomes for AN.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.