ArticleItalian journal of pediatrics2021
Effects of delayed cord clamping on neonatal jaundice, phototherapy and early hematological status in term cesarean section.
Article in Italian journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Efficacy and safety of phototherapy for jaundice in full-term newborns: a meta-analysis.Frontiers in pediatrics · 2025Pooled it
- Effect of administration routes of oxytocin on hemoglobin in neonates with delayed umbilical cord clamping: a multi-centre randomized controlled clinical trial.Archives of gynecology and obstetrics · 2024Trial
- Delayed versus early umbilical cord clamping for near-term infants born to preeclamptic mothers; a randomized controlled trial.BMC pregnancy and childbirth · 2022Trial
- Nomogram for predicting early hypophosphatemia in term infants.BMC pediatrics · 2024Article
- Comparing delayed cord clamping and umbilical cord milking during elective cesarean section for the neonatal outcome.European journal of obstetrics & gynecology and reproductive biology: X · 2023Article
- New insights in pediatrics in 2021: choices in allergy and immunology, critical care, endocrinology, gastroenterology, genetics, haematology, infectious diseases, neonatology, neurology, nutrition, palliative care, respiratory tract illnesses and telemedicine.Italian journal of pediatrics · 2022Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundDelayed cord clamping in full-term neonates is widely recommended, while in practice, it is rarely implemented in cesarean section due to the fear of neonatal jaundice and excessive maternal blood loss. The optimal timing of cord clamping remains uncertain. This study was to fully evaluate the effects of delayed cord clamping on short-term hematological status and jaundice in term neonates delivered by cesarean section.
methodsThis retrospective study enrolled 796 women, who were allocated into the early cord clamping group (n = 377) and the delayed cord clamping group (n = 419). The latter group was further divided into two subgroups (30-60 s, 61-120 s). The outcomes were neonatal transcutaneous bilirubin levels on 0 to 5 days of life and the rate of phototherapy. For neonates who had blood tests on the first three days of life, their hemoglobin and hematocrit were compared among groups.
resultsCompared with the early cord clamping group, delayed cord clamping merely increased the transcutaneous bilirubin level of neonates on the day of birth rather than that on the following five days. The heel peripheral blood sample size of 1-3 days in the early cord clamping group was 61, 25 and 33, and in the delayed cord clamping group was 53, 46 and 32, respectively. Delayed cord clamping at 30-60 s resulted in the higher neonatal hemoglobin level on day 3 and an increased rate of neonatal polycythemia, without a higher rate of phototherapy. Delayed cord clamping beyond 60 s did not further improve hematological status in term neonates born by cesarean section.
conclusionIn cesarean section, delayed cord clamping for 30-60 s improved the early hematological status of term neonates without the enhanced requirement of phototherapy for neonatal jaundice.
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