Evidence map›Paper›PMID 34039378›Full record

ArticleJournal of orthopaedic surgery and research2021

Histological and ultrastructural degenerative findings in the gluteus medius tendon after hip arthroplasty.

Mustafa Ibrahim, Urban Hedlundh, Ninni Sernert, Khaled Meknas, Lars Haag, Tomas Movin, Nikos Papadogiannakis, Jüri-Toomas Kartus

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of orthopaedic surgery and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Mustafa IbrahimDepartment of Orthopedics, Region Västra Götaland, NU Hospital Group, Trollhättan / Uddevalla, Sweden. mustafa.ibrahim.ahmad@vgregion.se.ORCID http://orcid.org/0000-0002-2294-5430
Urban HedlundhDepartment of Orthopedics, Region Västra Götaland, NU Hospital Group, Trollhättan / Uddevalla, Sweden.
Ninni SernertDepartment of Orthopedics, Region Västra Götaland, NU Hospital Group, Trollhättan / Uddevalla, Sweden.
Khaled MeknasDepartment of Orthopedics, University Hospital North Norway, N-9038, Tromsø, Norway.
Lars HaagDepartment of Laboratory Medicine, Division of Pathology, Karolinska Institutet, Stockholm, Sweden.
Tomas MovinDepartment of Clinical Science, Intervention and Technology, Division of Orthopedics and Biotechnology, Karolinska Institutet, Stockholm, Sweden.
Nikos PapadogiannakisDepartment of Laboratory Medicine, Division of Pathology, Karolinska Institutet, Stockholm, Sweden.
Jüri-Toomas KartusDepartment of Orthopedics, Region Västra Götaland, NU Hospital Group, Trollhättan / Uddevalla, Sweden.
Region Västra Götaland · SEKarolinska Institutet · SEUniversity Hospital of North Norway · NO

Funding

Västra Götalandsregionen ALFGBG-673881
6 · The paper itself

Abstract

backgroundDespite gluteus medius (GMED) tendinosis being relatively common, its presence in association with hip osteoarthritis (OA) or total hip arthroplasty (THA) is not well studied. It was hypothesized that more tendon degeneration would be found in patients with OA of the hip and in those that had undergone THA than that in a control group.

methodsOne hundred patients were included between 2016 and 2019 and were included into 4 groups; the patients were undergoing revision surgery in two groups and primary THA in the other two groups; 22 patients had previously undergone primary THA through a direct lateral approach (involving sectioning of the GMED tendon), 24 patients had previously undergone primary THA through a posterior approach (leaving the GMED tendon intact), 29 patients had primary hip OA, and 25 patients who suffered a femoral neck fracture served as controls. Biopsies from the GMED tendon were obtained at the time of the primary THA or the hip revision surgery. The tendon biopsies were examined ultrastructurally and histologically.

resultsUltrastructurally, the direct lateral and posterior revision groups had statistically significantly more collagen fibrils with smaller diameters compared with the fracture and primary THA groups. Moreover, the direct lateral revision group had more collagen fibrils with smaller diameters compared with the posterior revision group. Histologically, the direct lateral revision group had a higher total degeneration score (TDS) compared with the primary hip OA group.

conclusionsThe GMED tendon shows more ultrastructural degeneration in patients who undergo hip revision arthroplasty than in patients with primary OA of the hip and control patients, who had suffered a femoral neck fracture. Furthermore, patients who had previously undergone primary THA through a direct lateral approach revealed more histological GMED tendon degeneration than patients who suffer primary hip OA.

Indexed as

Arthroplasty, Replacement, HipAgedAged, 80 and overButtocksCase-Control StudiesFemaleFemoral Neck FracturesHumansMaleMicroscopy, Electron, TransmissionMiddle AgedMuscle, SkeletalOsteoarthritis, HipPostoperative ComplicationsTendonsGluteus mediusHip arthroplastyHip replacementTendinopathyTendinosis

Identifiers

PMID34039378
PMCPMC8152320
OpenAlexW3164627430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.