Evidence map›Paper›PMID 34039341›Full record

ArticleBMC women's health2021

Comparison of cervical cancer screening by self-sampling papillomavirus test versus pap-smear in underprivileged women in France.

Laura Reques, Camille Rolland, Anne Lallemand, Najat Lahmidi, Ezequiel Aranda-Fernández, Antonio Lazzarino, Julie Bottero, Françoise Hamers, Christine Bergeron, Ken Haguenoer and 2 more

2 registry-linked trialsOpen access · goldAbstract readControlled Clinical Trial
In one paragraph

Article in BMC women's health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03118258 naunknown statusnot on this map

Improving Access to Cervical Cancer Screening for Women Living in Precarious Conditions Met Within Doctors of the World Programs

TypeinterventionalSponsorMédecins du MondeRan2017 to 2019Enrolled1,258ConditionsUterine Cervical NeoplasmsArms'Pap smear' arm, 'Self-collected vaginal swab for HPV testing + pap smear triage' arm
NCT06656611 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

PAPMOBILE: Mobile Outreach Screening of High-Risk Human Papillomavirus Infection in Women with Limited Access to Health Services in Seine-Saint-Denis (greater Paris Area, France)

TypeinterventionalSponsorInstitut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'BaRan2024 to 2026Enrolled700ConditionsWomen's Health: Cervical NeoplasmArmsHPV self sampling
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Laura RequesMédecins du Monde, 62 rue Marcadet, 75018, Paris, France. requeslaura@hotmail.com.ORCID 0000-0003-1589-8012
Camille RollandMédecins du Monde, 62 rue Marcadet, 75018, Paris, France.
Anne LallemandMédecins du Monde, 62 rue Marcadet, 75018, Paris, France.
Najat LahmidiMédecins du Monde, 62 rue Marcadet, 75018, Paris, France.
Ezequiel Aranda-FernándezMédecins du Monde, 62 rue Marcadet, 75018, Paris, France.
Antonio LazzarinoEPISTATA - Agency for Clinical Research and Medical Statistics, London, UK.
Julie BotteroUnité de Maladies Infectieuses et Tropicales, Groupe Hospitalo-Universitaire Paris Seine St-Denis, AP-HP, Hôpital Jean Verdier, Bondy, France.
Françoise HamersSanté Publique France (National Public Health Agency), Saint Maurice cedex, France.
Christine BergeronLaboratoire CERBA, Saint-Ouen-l'Aumône, France.
Ken HaguenoerU1153, INSERM, Paris, France.
Guy LaunoyCentre François Baclesse, INSERM, Avenue du Général Harris, 14076, Caen, France.
Niklas LuhmannMédecins du Monde, 62 rue Marcadet, 75018, Paris, France.
Assistance Publique – Hôpitaux de Paris · FRInformation and Communication Technology Agency · LKInserm · FRMédecins du Monde · BESanté Publique France · FRUniversité de Tours · FRVirbac (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to compare cervical cancer screening by pap smear (PS) versus preliminary HPV testing based on self-collected samples (SC-HPV).

methodsInterventional study among underprivileged women from 25 to 65 years old in four French cities. The control group (CG) was referred for a PS. The experimental group (EG) conducted a SC-HPV test followed by a PS in case of positivity. Differences on screening completion and cytological abnormalities were analysed by logistic and Cox regression.

results383 women were assigned to the EG and 304 to the CG. The screening completion proportion was 39.5% in the CG compared to 71.3% in the EG (HR = 2.48 (CI 95% [1.99-3.08]; p < 0.001). The proportion of cytological abnormalities was 2.0% in the CG and 2.3% in the EG (OR = 1.20 (CI 95% [0.42-3.40]; p = 0.7). The proportion of participants lost to follow-up was 60.5% in the CG and 63.2% in the EG HPV positive (p = 0.18).

conclusionProviding an SC-HPV-test increased the participation of underprivileged women in CCS. Nevertheless, the significant number of lost to follow-up in both groups can undermine the initial benefits of the strategy for HPV positive women. Registration: Clinicaltrials.gov: NCT03118258.

Indexed as

Papillomavirus InfectionsUterine Cervical NeoplasmsAdultAgedEarly Detection of CancerFemaleFranceHumansMass ScreeningMiddle AgedPapanicolaou TestPapillomaviridaeVaginal SmearsCervical cancerPapillomavirusSC-HPVScreeningVulnerability

Identifiers

PMID34039341
PMCPMC8157706
OpenAlexW3164687330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.