Evidence map›Paper›PMID 34039086›Full record

ArticleSports health

Exercise-Induced Muscle Damage in Postmenopausal Well-Trained Women.

Nuria Romero-Parra, Cristina Maestre-Cascales, Nuria Marín-Jiménez, Beatriz Rael, Victor M Alfaro-Magallanes, Rocío Cupeiro, Ana B Peinado

Open access · greenAbstract read
In one paragraph

Article in Sports health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nuria Romero-ParraLFE Research Group. Department of Health and Human Performance, Faculty of Physical Activity and Sports Science, Universidad Politécnica de Madrid (UPM), Madrid, Spain.
Cristina Maestre-CascalesLFE Research Group. Department of Health and Human Performance, Faculty of Physical Activity and Sports Science, Universidad Politécnica de Madrid (UPM), Madrid, Spain.
Nuria Marín-JiménezGALENO Research Group, Department of Physical Education. Faculty of Education Sciences, Biomedical Research and Innovation Institute of Cádiz (INiBICA), University of Cádiz, Cádiz, Spain.
Beatriz RaelLFE Research Group. Department of Health and Human Performance, Faculty of Physical Activity and Sports Science, Universidad Politécnica de Madrid (UPM), Madrid, Spain.
Victor M Alfaro-MagallanesLFE Research Group. Department of Health and Human Performance, Faculty of Physical Activity and Sports Science, Universidad Politécnica de Madrid (UPM), Madrid, Spain.
Rocío CupeiroLFE Research Group. Department of Health and Human Performance, Faculty of Physical Activity and Sports Science, Universidad Politécnica de Madrid (UPM), Madrid, Spain.
Ana B PeinadoLFE Research Group. Department of Health and Human Performance, Faculty of Physical Activity and Sports Science, Universidad Politécnica de Madrid (UPM), Madrid, Spain.
Universidad Politécnica de Madrid · ESUniversidad de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSex hormone deprivation derived from menopause may affect exercise-induced muscle damage (EIMD). No studies have previously evaluated this response between postmpenopausal and premenopausal eumenorrheic women over the menstrual cycle. HYPOTHESIS: Postmenopausal women will present higher EIMD markers than premenopausal women, especially in comparison with the menstrual cycle phases where sex hormone concentrations are higher. STUDY

designCross-sectional study. LEVEL OF EVIDENCE: Level 3.

methodsThirteen postmenopausal and 19 eumenorrheic women, all of them resistance-trained, performed an eccentric squat-based exercise. The postmenopausal group performed 1 bout of exercise, while the eumenorrheic group performed 3 bouts coinciding with the early follicular, late follicular, and mid-luteal phases ot their menstrual cycle. Muscle soreness, countermovement jump, creatine kinase (CK), myoglobin, lactate dehydrogenase, interleukin-6, tumor necrosis factor-α, and C-reactive protein were evaluated before and postexercise.

resultsThe expected differences in sex hormones were observed between groups (

conclusionDespite higher resting levels of myoglobin and lower strength values in postmenopausal than in premenopausal women, EIMD was similar between both reproductive profiles. This suggests a potential benefit of being physically active despite aging and sex hormone deprivation. CLINICAL RELEVANCE: Sex hormone deprivation derived from menopause seems not to influence muscle damage reponse to eccentric exercise in resistance-trained postmenopausal women.

Indexed as

Muscle, SkeletalPostmenopauseCross-Sectional StudiesExerciseFemaleHumansMyalgiacreatine kinaseeccentric exerciseinflammationmenopauseresistancesex hormones

Identifiers

PMID34039086
PMCPMC8558998
OpenAlexW3165365596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.