Evidence map›Paper›PMID 34039024›Full record

ArticleJournal of neurotrauma2021

Regional White Matter Diffusion Changes Associated with the Cumulative Tensile Strain and Strain Rate in Nonconcussed Youth Football Players.

James M Holcomb, Ryan A Fisicaro, Logan E Miller, Fang F Yu, Elizabeth M Davenport, Yin Xi, Jillian E Urban, Ben C Wagner, Alexander K Powers, Christopher T Whitlow and 2 more

Abstract read
In one paragraph

Article in Journal of neurotrauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  8. Review
  9. Article
  10. White matter hyperintensities in former American football players.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

James M HolcombUniversity of Texas Southwestern Medical Center, Dallas, Texas, USA.
Ryan A FisicaroUniversity of Texas Southwestern Medical Center, Dallas, Texas, USA.
Logan E MillerWake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Fang F YuUniversity of Texas Southwestern Medical Center, Dallas, Texas, USA.
Elizabeth M DavenportUniversity of Texas Southwestern Medical Center, Dallas, Texas, USA.
Yin XiUniversity of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jillian E UrbanWake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Ben C WagnerUniversity of Texas Southwestern Medical Center, Dallas, Texas, USA.
Alexander K PowersWake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Christopher T WhitlowWake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Joel D StitzelWake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Joseph A MaldjianUniversity of Texas Southwestern Medical Center, Dallas, Texas, USA.

Funding

Biomechanical Basis of Pediatric mTBI Due to Sports Related ConcussionR01NS094410 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI DUMA, STEFAN, GREENWALD, RICHARD M · 2015 to 2019
$3.3M
iTAKL: Imaging Telemetry And Kinematic modeLing in youth footballR01NS082453 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI GIOIA, GERARD A., MALDJIAN, JOSEPH A · 2014 to 2018
$3.3M
NINDS NIH HHS R01 NS082453NINDS NIH HHS R01 NS094410
6 · The paper itself

Abstract

The purpose of this study is to assess the relationship between regional white matter diffusion imaging changes and finite element strain measures in nonconcussed youth football players. Pre- and post-season diffusion-weighted imaging was performed in 102 youth football subject-seasons, in which no concussions were diagnosed. The diffusion data were normalized to the IXI template. Percent change in fractional anisotropy (%ΔFA) images were generated. Using data from the head impact telemetry system, the cumulative maximum principal strain one times strain rate (CMPS1

Indexed as

AdolescentAge FactorsAnisotropyBrain ConcussionCase-Control StudiesChildCohort StudiesDiffusion Magnetic Resonance ImagingFootballHumansMaleWhite MatterDTIFAfootballnonconcussedstrainstrain ratewhite matteryouth

Identifiers

PMID34039024
PMCPMC8820832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.