Evidence map›Paper›PMID 34039021›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2021

Homocysteine Is Associated With Future Venous Thromboembolism in 2 Prospective Cohorts of Women.

Aaron W Aday, Edward K Duran, Martin Van Denburgh, Eunjung Kim, William G Christen, JoAnn E Manson, Paul M Ridker, Aruna D Pradhan

Open access · bronzeAbstract read
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

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  13. Body Iron Store and its Association with Risk of First Episode of Spontaneous Lower Extremity Deep Vein Thrombosis/ Pulmonary Embolism: A Case-Control Study.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2023
    Article
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  15. Thrombophilia and outcomes of venous thromboembolism in older patients.Research and practice in thrombosis and haemostasis · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Aaron W AdayDivision of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (A.W.A., E.K.D., M.V.D., E.K., W.G.C., J.E.M., P.M.R., A.D.P.).
Edward K DuranDivision of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (A.W.A., E.K.D., M.V.D., E.K., W.G.C., J.E.M., P.M.R., A.D.P.).
Martin Van DenburghDivision of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (A.W.A., E.K.D., M.V.D., E.K., W.G.C., J.E.M., P.M.R., A.D.P.).
Eunjung KimDivision of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (A.W.A., E.K.D., M.V.D., E.K., W.G.C., J.E.M., P.M.R., A.D.P.).
William G ChristenDivision of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (A.W.A., E.K.D., M.V.D., E.K., W.G.C., J.E.M., P.M.R., A.D.P.).
JoAnn E MansonDivision of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (A.W.A., E.K.D., M.V.D., E.K., W.G.C., J.E.M., P.M.R., A.D.P.).
Paul M RidkerDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (P.M.R.).
Aruna D PradhanDivision of Cardiovascular Medicine, VA Boston Medical Center, Boston, MA (A.D.P.).
Brigham and Women's Hospital · USBoston Medical Center · US

Funding

Women's Health Study: Continued Follow-upR01CA047988 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E., LEE, I-MIN · 1991 to 2014
$28.2M
Training Program in the Epidemiology of CVDT32HL007575 · NHLBI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI BURING, JULIE E., RIDKER, PAUL M. · 1985 to 2019
$5.0M
Women's Health Study: Continued Follow-UpR01HL080467 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E. · 2005 to 2010
$4.5M
Women's Health Study: Infrastructure support for continued cohort follow-upU01CA182913 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E., LEE, I-MIN · 2019 to 2023
$4.0M
The Women's Health Study: Infrastructure Support for Continued Cohort Follow-upUM1CA182913 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E., LEE, I-MIN · 2014 to 2018
$4.0M
The Vanderbilt Emergency Care Research Training ProgramK12HL133117 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STORROW, ALAN B · 2016 to 2020
$1.9M
TRIAL OF VITAMIN E, BETA-CAROTENE &ASPRIN IN WOMENR01HL043851 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E · 1991 to 2000
$1.6M
The Women's Health Study: Addition of New Data to Maximize its Research ImpactRC1HL099355 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E. · 2009 to 2010
$992k
The Impact of Thrombosis and Antithrombotic Therapy on Peripheral Artery DiseaseK23HL151871 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ADAY, AARON W. · 2021 to 2025
$927k
New Gene Discoveries and Biology of Ribosomes in Diamond-Blackfan AnemiaK02HL111156 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI GAZDA, HANNA TERESA · 2012 to 2016
$568k
NCI NIH HHS R01 CA047988NCI NIH HHS U01 CA182913NCI NIH HHS UM1 CA182913NHLBI NIH HHS K02 HL111156NHLBI NIH HHS K12 HL133117NHLBI NIH HHS K23 HL151871NHLBI NIH HHS R01 HL043851NHLBI NIH HHS R01 HL080467NHLBI NIH HHS RC1 HL099355NHLBI NIH HHS T32 HL007575
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

AdultAge FactorsBiomarkersCase-Control StudiesFemaleHomocysteineHumansHyperhomocysteinemiaIncidenceMiddle AgedPrognosisProspective StudiesRandomized Controlled Trials as TopicRisk AssessmentRisk FactorsTime FactorsBiomarkersHomocysteinebiomarkerhomocysteineplasmapulmonary embolismvenous thromboembolism

Identifiers

PMID34039021
PMCPMC8222168
OpenAlexW3165357432

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.