Evidence map›Paper›PMID 34038879›Full record

ArticlePhysiological measurement2021

Peaks and valleys: oscillatory cerebral blood flow at high altitude protects cerebral tissue oxygenation.

Garen K Anderson, Alexander J Rosenberg, Haley J Barnes, Jordan Bird, Brandon Pentz, Britta R M Byman, Nicholas Jendzjowsky, Richard J A Wilson, Trevor A Day, Caroline A Rickards

Open access · greenAbstract read
In one paragraph

Article in Physiological measurement, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. A systematic review, meta-analysisJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Pooled it
  2. Review
  3. Article
  4. Article
  5. High-resolution vasomotion analysis reveals novel arteriole physiological features and progressive modulation of cerebral vascular networks by stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  6. Article
  7. CaCommunications biology · 2024
    Article
  8. Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Garen K AndersonCerebral and Cardiovascular Physiology Laboratory, Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, TX, United States of America.ORCID 0000-0002-1013-3478
Alexander J RosenbergCerebral and Cardiovascular Physiology Laboratory, Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, TX, United States of America.
Haley J BarnesCerebral and Cardiovascular Physiology Laboratory, Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, TX, United States of America.
Jordan BirdDepartment of Biology, Mount Royal University, Calgary, Alberta, Canada.ORCID 0000-0003-2548-6468
Brandon PentzDepartment of Biology, Mount Royal University, Calgary, Alberta, Canada.
Britta R M BymanDepartment of Biology, Mount Royal University, Calgary, Alberta, Canada.
Nicholas JendzjowskyInstitute of Respiratory Medicine & Exercise Physiology, The Lundquist Institute at UCLA Harbor Medical, Torrance, CA, United States of America.
Richard J A WilsonHotchkiss Brain Institute and Alberta Children's Hospital Research Institute; Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
Trevor A DayDepartment of Biology, Mount Royal University, Calgary, Alberta, Canada.
Caroline A RickardsCerebral and Cardiovascular Physiology Laboratory, Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, TX, United States of America.
Mount Royal University · CAUniversity of North Texas · USAlberta Children's Hospital · CAUCLA Medical Center · US

Funding

Training in the Neurobiology of Aging and Alzheimer's DiseaseT32AG020494 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI ROBERT Clinton BARBER, NATHALIE SUMIEN · 2002 to 2026
$6.9M
Development of a clinically-relevant test for assessment of cerebral vascular functionF32HL144082 · NHLBI · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI ROSENBERG, ALEXANDER · 2019 to 2021
$149k
Potential Therapeutic Benefits of Remote Ischemic Preconditioning vs. Occlusive Exercise-an acute studyF31HL134242 · NHLBI · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI SPRICK, JUSTIN DANIEL · 2017 to 2017
$28k
American Heart Association-American Stroke Association 17GRNT33671110NHLBI NIH HHS F31 HL134242NHLBI NIH HHS F32 HL144082NIA NIH HHS T32 AG020494
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AltitudeCerebrovascular CirculationBlood Flow VelocityBlood PressureFemaleHumansHypovolemiaMaleMiddle Cerebral ArteryPerfusioncerebral blood flowhemodynamic oscillationshypoxia

Identifiers

PMID34038879
PMCPMC11046575
OpenAlexW3163964514

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.