ArticleAmerican journal of respiratory and critical care medicine2021
Association between Troponin I Levels during Sepsis and Postsepsis Cardiovascular Complications.
Open access · greenAbstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Cardiac troponin as a prognosticator of mortality in patients with sepsis: A systematic review and meta-analysis.Immunity, inflammation and disease · 2023Pooled it
- Machine learning-based prediction of 1-year mortality risk after off-pump coronary artery bypass grafting.Journal of thoracic disease · 2026Article
- Development and validation of a clinical prediction model for sepsis-induced cardiomyopathy.Frontiers in cardiovascular medicine · 2026Article
- Predictive Value of Cardiac Troponin Combined with p-SOFA Score in Sepsis Children with PCIS ≥ 70.International journal of general medicine · 2026Article
- Cardiac Troponin I as a Prognostic Indicator of Mortality in Patients With Sepsis and Organ Dysfunction.Cureus · 2026Article
- Impact of 30 mL/kg fluid resuscitation completed within one hour on elderly septic shock patient.Annals of medicine · 2025Observational
- Troponin elevation in sepsis: when numbers mislead and clinical context matters.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025Article
- Beyond Acute Coronary Syndromes: Troponins as Diagnostic and Prognostic Tools in Heart Failure.Biomedicines · 2025Review
- Inflammatory Profile and Risk of Post-Intervention Infection in Relation to Myocardial Necrosis Markers.Healthcare (Basel, Switzerland) · 2025Article
- Long-term cardiovascular outcomes and risk factors in adult sepsis survivors: a systematic review and meta-analysis.World journal of emergency medicine · 2025Review
- From cardiac injury to omics signatures: a narrative review on biomarkers in septic cardiomyopathy.Clinical and experimental medicine · 2025Review
- Impact of Elevated Troponin Level at the Time of Sepsis Recognition on the Clinical Outcomes: A Propensity Score-Matched Cohort Study.Journal of the American Heart Association · 2025Article
- Prognostic analysis of sepsis-induced myocardial injury patients using propensity score matching and doubly robust analysis with machine learning-based risk prediction model development.Frontiers in medicine · 2025Article
- Predicting stroke risk after sepsis hospitalization with new-onset atrial fibrillation.Journal of hospital medicine · 2024Article
- Intravenous Opioid Administration During Mechanical Ventilation and Use After Hospital Discharge.JAMA network open · 2024Article
- PLD2 deletion ameliorates sepsis-induced cardiomyopathy by suppressing cardiomyocyte pyroptosis via the NLRP3/caspase 1/GSDMD pathway.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024Article
- Variation in Sedative and Analgesic Use During the COVID-19 Pandemic and Associated Outcomes.CHEST critical care · 2024Article
- Clinical Interpretation of Serum Troponin in the Era of High-Sensitivity Testing.Diagnostics (Basel, Switzerland) · 2024Review
- Comprehensive temporal analysis of right ventricular function and pulmonary haemodynamics in mechanically ventilated COVID-19 ARDS patients.Annals of intensive care · 2024Article
- Acute Myocardial Injury Assessed by High-Sensitivity Cardiac Troponin I Levels in Adult Patients with Early Sepsis at a Tertiary Referral Center in Mexico: An Exploratory Study.Journal of cardiovascular development and disease · 2024Article
Corrections and comments
- Commented on by
Authors and funding
14 authors at 3 institutions in 1 country.
Michael A GarciaThe Pulmonary Center, Section of Pulmonary, Allergy, Sleep, and Critical Care, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.ORCID 0000-0001-6504-2234
Justin M RucciThe Pulmonary Center, Section of Pulmonary, Allergy, Sleep, and Critical Care, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.ORCID 0000-0002-6400-6060
Khanh K ThaiDivision of Research, Kaiser Permanente Northern California, Oakland, California.
Yun LuDivision of Research, Kaiser Permanente Northern California, Oakland, California.
Patricia KipnisDivision of Research, Kaiser Permanente Northern California, Oakland, California.
Alan S GoDivision of Research, Kaiser Permanente Northern California, Oakland, California.
Manisha DesaiQuantitative Sciences Unit, Center for Biomedical Informatics Research, Department of Medicine, and.
Nicholas A BoschThe Pulmonary Center, Section of Pulmonary, Allergy, Sleep, and Critical Care, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.
Adriana MartinezDivision of Research, Kaiser Permanente Northern California, Oakland, California.
Heather ClancyDivision of Research, Kaiser Permanente Northern California, Oakland, California.
Ycar DevisThe Pulmonary Center, Section of Pulmonary, Allergy, Sleep, and Critical Care, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.
Laura C MyersDivision of Research, Kaiser Permanente Northern California, Oakland, California.ORCID 0000-0002-2872-3388
Vincent X LiuDivision of Research, Kaiser Permanente Northern California, Oakland, California.
Allan J WalkeyThe Pulmonary Center, Section of Pulmonary, Allergy, Sleep, and Critical Care, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.
Kaiser Permanente · USPulmonary and Allergy Associates · USStanford University · US
Funding
BIOLOGY OF THE LUNG--MULTIDISCIPLINARY PROGRAMT32HL007035 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Darrell N. Kotton, JOSEPH P MIZGERD · 1985 to 2026
$24.3MBoston Biomedical Innovation CenterU54HL119145 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLAN, DAVID E., LOSCALZO, JOSEPH · 2013 to 2021
$18.8MTargeting cardiovascular events to improve patient outcomes after sepsisR01HL139751 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WALKEY, ALLAN J. · 2018 to 2021
$2.8MEvaluating Routine Opioid Use during Acute Respiratory FailureR01HL151607 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LIU, VINCENT, WALKEY, ALLAN J. · 2020 to 2023
$2.3MAutomated detection and prediction of atrial fibrillation during sepsisR01HL136660 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WALKEY, ALLAN J. · 2017 to 2020
$2.2MAdvanced Risk Adjusters and Predictive Formulas for ICD-10 Based Risk AdjustmentR01HS026485 · AHRQ · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI ELLIS, RANDALL P. · 2018 to 2020
$1.2MAHRQ HHS R01 HS026485NHLBI NIH HHS R01 HL136660NHLBI NIH HHS R01 HL139751NHLBI NIH HHS R01 HL151607NHLBI NIH HHS T32 HL007035NHLBI NIH HHS U54 HL119145
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdultAgedAged, 80 and overBiomarkersCohort StudiesFemaleHeart DiseasesHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsSepsisSurvivorsTime FactorsBiomarkersTroponin Icardiovascular riskinfectionmortalitysepsistroponin
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.