Evidence map›Paper›PMID 34038637›Full record

ArticleAnalytical chemistry2021

On-Chip Cyclic Voltammetry Measurements Using a Compact 1024-Electrode CMOS IC.

Meng Huang, Carlos I Dorta-Quiñones, Bradley A Minch, Manfred Lindau

Abstract read
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Surface-modified CMOS biosensors.Frontiers in bioengineering and biotechnology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meng HuangSchool of Applied & Engineering Physics, Cornell University, Ithaca, New York 14853, United States.
Carlos I Dorta-QuiñonesSchool of Electrical & Computer Engineering, Cornell University, Ithaca, New York 14853, United States.
Bradley A MinchFranklin W. Olin College of Engineering, Needham, Massachusetts 02492, United States.
Manfred LindauSchool of Applied & Engineering Physics, Cornell University, Ithaca, New York 14853, United States.ORCID 0000-0002-5722-9557

Funding

Molecular mechanisms of exocytotic vesicle fusion and release.R35GM139608 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LINDAU, MANFRED · 2021 to 2025
$1.9M
Scalable sensor array platform for analysis of quantal transmitter release eventsR01MH095046 · NIMH · CORNELL UNIVERSITY · PI LINDAU, MANFRED · 2011 to 2014
$1.5M
Scalable amperometric microchip array for high-throughput screening of small molecules, peptides or genetic perturbations for modulation of quantal transmitter releaseR43MH109212 · NIMH · EXOCYTRONICS, LLC · PI LINDAU, MANFRED, LIU, XIN ALICE · 2016 to 2017
$869k
NIGMS NIH HHS R35 GM139608NIMH NIH HHS R01 MH095046NIMH NIH HHS R43 MH109212
6 · The paper itself

Abstract

Complementary metal-oxide-semiconductor (CMOS) microelectrode arrays integrate amplifier arrays with on-chip electrodes, offering high-throughput platforms for electrochemical sensing with high spatial and temporal resolution. Such devices have been developed for highly parallel constant voltage amperometric detection of transmitter release from multiple cells with single-vesicle resolution. Cyclic voltammetry (CV) is an electrochemical method that applies voltage waveforms, which provides additional information about electrode properties and about the nature of analytes. A 16-channel, 64-electrode-per-channel CMOS integrated circuit (IC) fabricated in a 0.5 μm CMOS process for CV is demonstrated. Each detector consists of only 11 transistors and an integration capacitor with a unit dimension of 0.0015 mm

Indexed as

Electrochemical TechniquesSemiconductorsDopamineMicroelectrodesOxidesDopamineOxides

Identifiers

PMID34038637
PMCPMC8650766

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.