Evidence map›Paper›PMID 34038243›Full record

ArticleAmerican journal of physiology. Cell physiology2021

Human adrenal glomerulosa cells express K2P and GIRK potassium channels that are inhibited by ANG II and ACTH.

John J Enyeart, Judith A Enyeart

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

John J EnyeartDepartment of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Judith A EnyeartDepartment of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, Ohio.
The Ohio State University Wexner Medical Center · US

Funding

Properties of Ion Channels that Control SecretionR56DK047875 · NIDDK · OHIO STATE UNIVERSITY · PI ENYEART, JOHN J · 2010 to 2010
$229k
NIDDK NIH HHS R56 DK047875
6 · The paper itself

Abstract

In whole cell patch clamp recordings, it was discovered that normal human adrenal zona glomerulosa (AZG) cells express members of the three major families of K

Indexed as

AdolescentAdrenocorticotropic HormoneAdultAldosteroneAngiotensin IIArachidonic AcidAutopsyChildColforsinFemaleGene ExpressionG Protein-Coupled Inwardly-Rectifying Potassium ChannelsHumansKv1.4 Potassium ChannelMaleMembrane PotentialsAdrenocorticotropic HormoneAldosteroneAngiotensin IIArachidonic AcidColforsinG Protein-Coupled Inwardly-Rectifying Potassium ChannelsKCNA4 protein, humanKCNJ5 protein, humanKv1.4 Potassium ChannelNerve Tissue Proteinspotassium channel protein TREK-1Potassium Channels, Tandem Pore Domainpotassium channel subfamily K member 3ACTHangiotensin IIhuman adrenal glomerulosaKCNJ5TREK-1

Identifiers

PMID34038243
PMCPMC8321792
OpenAlexW3164103701

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.