Evidence map›Paper›PMID 34038225›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2021

Improved osteogenesis in rat femur segmental defects treated with human allograft and zinc adjuvants.

Deboleena Kanjilal, Christopher Grieg, Maya Deza Culbertson, Sheldon S Lin, Michael Vives, Joseph Benevenia, J Patrick O'Connor

Open access · greenAbstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Introduction to the Regenerative Medicine Thematic Issue.Experimental biology and medicine (Maywood, N.J.) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Deboleena KanjilalDepartment of Orthopaedics, Rutgers-New Jersey Medical School, Newark, NJ 07103, USA.
Christopher GriegDepartment of Orthopaedics, Rutgers-New Jersey Medical School, Newark, NJ 07103, USA.
Maya Deza CulbertsonDepartment of Orthopaedics, Rutgers-New Jersey Medical School, Newark, NJ 07103, USA.
Sheldon S LinDepartment of Orthopaedics, Rutgers-New Jersey Medical School, Newark, NJ 07103, USA.
Michael VivesDepartment of Orthopaedics, Rutgers-New Jersey Medical School, Newark, NJ 07103, USA.
Joseph BeneveniaDepartment of Orthopaedics, Rutgers-New Jersey Medical School, Newark, NJ 07103, USA.
J Patrick O'ConnorDepartment of Orthopaedics, Rutgers-New Jersey Medical School, Newark, NJ 07103, USA.ORCID 0000-0003-0282-1104
Rutgers, The State University of New Jersey · US

Funding

COX-2 Functions in Bone Fracture HealingR01AR069044 · NIAMS · RBHS-NEW JERSEY MEDICAL SCHOOL · PI O'CONNOR, J PATRICK · 2016 to 2020
$2.1M
NIAMS NIH HHS R01 AR069044
6 · The paper itself

Abstract

Bone allograft is widely used to treat large bone defects or complex fractures. However, processing methods can significantly compromise allograft osteogenic activity. Adjuvants that can restore the osteogenic activity of processed allograft should improve clinical outcomes. In this study, zinc was tested as an adjuvant to increase the osteogenic activity of human allograft in a

Indexed as

AllograftsAnimalsBone MatrixBone TransplantationCancellous BoneFemurHumansOsteogenesisRatsTransplantation, HomologousZincZincallograftbone regenerationRag2ratZinc

Identifiers

PMID34038225
PMCPMC8381705
OpenAlexW3164450107

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.