Evidence map›Paper›PMID 34038132›Full record

ArticleJournal of natural products2021

Sinularamides A-G, Terpenoid-Derived Spermidine and Spermine Conjugates with Casitas B-Lineage Lymphoma Proto-Oncogene B (Cbl-b) Inhibitory Activities from a

Wei Jiang, Dongdong Wang, Brice A P Wilson, Donna Voeller, Heidi R Bokesch, Emily A Smith, Stanley Lipkowitz, Barry R O'Keefe, Kirk R Gustafson

Open access · greenAbstract read
In one paragraph

Article in Journal of natural products, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Terpenoids from the Soft CoralMarine drugs · 2024
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Wei JiangMarine Science & Technology Institute, College of Environmental Science & Engineering, Yangzhou University, Yangzhou, Jiangsu 225127, People's Republic of China.
Dongdong WangMolecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702-1201, United States.ORCID 0000-0002-7824-2507
Brice A P WilsonMolecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702-1201, United States.ORCID 0000-0001-8988-1964
Donna VoellerWomen's Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, United States.
Heidi R BokeschMolecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702-1201, United States.
Emily A SmithMolecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702-1201, United States.
Stanley LipkowitzWomen's Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, United States.
Barry R O'KeefeMolecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702-1201, United States.ORCID 0000-0003-0772-4856
Kirk R GustafsonMolecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702-1201, United States.ORCID 0000-0001-6821-4943
Target (United States) · USLeidos (United States) · USNational Cancer Institute · US

Funding

Natural Products Discovery and Characterization Through Network CollaborationsZIABC011568 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI DU, LIN · 2014 to 2025
$17.2M
Cbl Proteins as Regulators of Tyrosine Kinase SignalingZIABC010977 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LIPKOWITZ, STANLEY · 2009 to 2025
$13.4M
Assay development and screening for molecular targets and discoveryZIABC011904 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WILSON, BRICE · 2019 to 2025
$12.8M
Cell-free assay technologies for the identification of active compoundsZIABC011471 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI OKEEFE, BARRY · 2012 to 2025
$12.4M
Isolation of bioactive proteins from natural product extractsZIABC011472 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI OKEEFE, BARRY · 2012 to 2025
$7.8M
CCR NIH HHS HHSN261200800001CIntramural NIH HHS ZIA BC011568NCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

An extract of a

Indexed as

Adaptor Proteins, Signal TransducingAnimalsAnthozoaMolecular StructurePalauProto-Oncogene Proteins c-cblSpermidineSpermineTerpenesAdaptor Proteins, Signal TransducingCBLB protein, humanProto-Oncogene Proteins c-cblSpermidineSpermineTerpenes

Identifiers

PMID34038132
PMCPMC9341130
OpenAlexW3164913172

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.