Evidence map›Paper›PMID 34038090›Full record

ArticleAnalytical chemistry2021

Multiomics Imaging Using High-Energy Water Gas Cluster Ion Beam Secondary Ion Mass Spectrometry [(H

Hua Tian, Sadia Sheraz Née Rabbani, John C Vickerman, Nicholas Winograd

Open access · hybridAbstract read
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
7.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Mass Spectrometry Imaging.Analytical chemistry · 2025
    Review
  8. Article
  9. The Static Limit in MeV Secondary Ion Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Spatial pharmacology using mass spectrometry imaging.Trends in pharmacological sciences · 2024
    Review
  16. Review
  17. Review
  18. Article
  19. Gold-Assisted Molecular Imaging of Organic Tissue by MeV Secondary Ion Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2023
    Article
  20. Exploring Single-Cell Exposomics by Mass Spectrometry.Environmental science & technology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Hua TianDepartment of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0002-3598-0219
Sadia Sheraz Née RabbaniThe Rosalind Franklin Institute, Harwell Campus, Didcot OX11 0FA, U.K.
John C VickermanManchester Institute of Biotechnology, University of Manchester, Manchester M1 7DN, U.K.
Nicholas WinogradDepartment of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Pennsylvania State University · USRosalind Franklin Institute · GBUniversity of Manchester · GB

Funding

Multimodal mass spectrometry imaging of mouse and human liverUG3CA256962 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI STOCKWELL, BRENT R., TIAN, HUA · 2020 to 2021
$600k
NCI NIH HHS UG3 CA256962
6 · The paper itself

Abstract

Integration of multiomics at the single-cell level allows the unambiguous dissecting of phenotypic heterogeneity at different states such as health, disease, and biomedical response. Imaging mass spectrometry holds the promise of being able to measure multiple types of biomolecules in parallel in the same cell. We have explored the possibility of using water gas cluster ion beam secondary ion mass spectrometry [(H

Indexed as

Spectrometry, Mass, Secondary IonWaterLipidsPhysical PhenomenaProteinsLipidsProteinsWater

Identifiers

PMID34038090
PMCPMC8190772
OpenAlexW3165302562

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.