ArticleACS applied materials & interfaces2021
Self-Powered Detection of Glucose by Enzymatic Glucose/Oxygen Fuel Cells on Printed Circuit Boards.
Article in ACS applied materials & interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 47 citations in OpenAlex.
- Sensitive electrochemical detection of total sugars in food using NiFe alloy nanowires.Mikrochimica acta · 2025Article
- Tuning Core Flexibility and Curvature in Azine-Linked Covalent Organic Frameworks for Attomolar-Level Impedimetric Sensing of Glucose.Journal of the American Chemical Society · 2025Article
- Current advances in multi-strategy collaborative sensitization for self-powered electrochemical biosensors and their applications in disease biomarker detection.Mikrochimica acta · 2025Review
- Robust Pt/Au Composite Nanostructures for Abiotic Glucose Sensing.Biosensors · 2025Article
- Self-powered wearable biosensor based on stencil-printed carbon nanotube electrodes for ethanol detection in sweat.Analytical and bioanalytical chemistry · 2024Article
- Schottky Interface Enabled Electrospun Rhodium Oxide Doped Gold for Both pH Sensing and Glucose Measurements in Neutral Buffer and Human Serum.Langmuir : the ACS journal of surfaces and colloids · 2024Article
- Soft-Template-Based Manufacturing of Gold Nanostructures for Energy and Sensing Applications.Biosensors · 2024Article
- Towards a Self-Powered Amperometric Glucose Biosensor Based on a Single-Enzyme Biofuel Cell.Biosensors · 2024Article
- Sensors for in situ monitoring of oral and dental health parameters in saliva.Clinical oral investigations · 2023Review
- Miniaturized Microfluidic Electrochemical Biosensors Powered by Enzymatic Biofuel Cell.Biosensors · 2023Review
- Lab-on-PCB: One step away from the accomplishment ofBiomicrofluidics · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Monitoring glucose levels in physiological fluids can help prevent severe complications associated with hypo- and hyper-glycemic events. Current glucose-monitoring systems require a three-electrode setup and a power source to function, which can hamper the system miniaturization to the patient discomfort. Enzymatic fuel cells (EFCs) offer the opportunity to develop self-powered and minimally invasive glucose sensors by eliminating the need for an external power source. Nevertheless, practical applications demand for cost-effective and mass-manufacturable EFCs compatible with integration strategies. In this study, we explore for the first time the use of gold electrodes on a printed circuit board (PCB) for the development of an EFC and demonstrate its application in saliva. To increase the specific surface area, the PCB gold-plated electrodes were modified with porous gold films. At the anode, glucose oxidase is immobilized with an osmium redox polymer that serves as an electron-transfer mediator. At the cathode, bilirubin oxidase is adsorbed onto the porous gold surface with a blocking agent that prevents parasitic reactions while maintaining the enzyme catalytic activity. The resulting EFC showed a linear response to glucose in phosphate buffer within the range 50 μM to 1 mM, with a sensitivity of 14.13 μA cm
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