Evidence map›Paper›PMID 34038028›Full record

ArticleCurrent protocols2021

Using the PhenX Toolkit to Select Standard Measurement Protocols for Your Research Study.

Lisa Ann Cox, Stephen Hwang, Jonathan Haines, Erin M Ramos, Catherine A McCarty, Mary L Marazita, Michelle L Engle, Tabitha Hendershot, Huaqin Helen Pan, Carol M Hamilton

Abstract read
In one paragraph

Article in Current protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Diet Quality of Older African Americans: Impact of Knowledge and Perceived Threat of COVID-19.International journal of environmental research and public health · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lisa Ann CoxRTI International, Research Triangle Park, North Carolina.
Stephen HwangRTI International, Research Triangle Park, North Carolina.
Jonathan HainesDepartment of Population & Quantitative Health Sciences, Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, Ohio.
Erin M RamosNational Human Genome Research Institute (NHGRI), Bethesda, Maryland.
Catherine A McCartyUniversity of Minnesota Medical School, Duluth Campus, Duluth, Minnesota.
Mary L MarazitaCenter for Craniofacial and Dental Genetics, Department of Oral and Craniofacial Sciences, School of Dental Medicine; Department of Human Genetics, Graduate School of Public Health; and Clinical and Translational Science, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Michelle L EngleRTI International, Research Triangle Park, North Carolina.
Tabitha HendershotRTI International, Research Triangle Park, North Carolina.
Huaqin Helen PanRTI International, Research Triangle Park, North Carolina.
Carol M HamiltonRTI International, Research Triangle Park, North Carolina.

Funding

Genomic Resource Grant for the PhenX Toolkit - expansion and sustainabilityPhenX Supplement for COVID-19 ResearchU41HG007050 · NHGRI · RESEARCH TRIANGLE INSTITUTE · PI HAMILTON, CAROL MARIE · 2013 to 2022
$21.2M
Adding Legacy Clinical Data to the Federal Interagency Traumatic Brain Injury (FIR03NS088021 · NINDS · RESEARCH TRIANGLE INSTITUTE · PI PAN, HUAQIN · 2014 to 2014
$147k
NCI NIH HHSNHGRI NIH HHS U41 HG007050NHLBI NIH HHSNIDA NIH HHSNIH HHS U41HG007050NIMHDNINDS NIH HHS R03 NS088021ODCDC CDC HHSOffice of Behavioral and Social Sciences Research
6 · The paper itself

Abstract

The goals of PhenX (consensus measures for Phenotypes and eXposures) are to promote the use of standard measurement protocols and to help investigators identify opportunities for collaborative research and cross-study analysis, thus increasing the impact of individual studies. The PhenX Toolkit (https://www.phenxtoolkit.org/) offers high-quality, well-established measurement protocols to assess phenotypes and exposures in studies with human participants. The Toolkit contains protocols representing 29 research domains and 6 specialty collections of protocols that add depth to the Toolkit in specific research areas (e.g., COVID-19, Social Determinants of Health [SDoH], Blood Sciences Research [BSR], Mental Health Research [MHR], Tobacco Regulatory Research [TRR], and Substance Abuse and Addiction [SAA]). Protocols are recommended for inclusion in the PhenX Toolkit by Working Groups of domain experts using a consensus process that includes input from the scientific community. For each PhenX protocol, the Toolkit provides a detailed description, the rationale for inclusion, and supporting documentation. Users can browse protocols in the Toolkit, search the Toolkit using keywords, or use Browse Protocols Tree to identify protocols of interest. The PhenX Toolkit provides data dictionaries compatible with the database of Genotypes and Phenotypes (dbGaP), Research Electronic Data Capture (REDCap) data submission compatibility, and data collection worksheets to help investigators incorporate PhenX protocols into their study design. The PhenX Toolkit provides resources to help users identify published studies that used PhenX protocols. © 2021 The Authors. Current Protocols published by Wiley Periodicals LLC. Basic Protocol: Using the PhenX Toolkit to support or extend study design.

Indexed as

Databases as TopicEnvironmental ExposureGenetic Predisposition to DiseaseGenome-Wide Association StudyHuman GeneticsHumansInterdisciplinary ResearchPhenotypeSoftwaredata collection protocolsenvironmental exposuresgenome-wide association studies (GWAS)phenotypesstandard measures

Identifiers

PMID34038028
PMCPMC8251725

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.