Evidence map›Paper›PMID 34037955›Full record

Trial reportIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2021

Effect of moderate aerobic exercises on symptoms of functional dyspepsia.

Siddhesh Vijay Rane, Bharati Asgaonkar, Pravin Rathi, Qais Contractor, Sanjay Chandnani, Parmeshwar Junare, Prasanta Debnath, Vidya Bhat

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Nurturing gut health: A comprehensive framework.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Review
  4. Physical Activity as a Therapeutic Strategy for Functional Dyspepsia.Journal of neurogastroenterology and motility · 2026
    Article
  5. Article
  6. Review
  7. Circadian regulation of gastrointestinal motility and the effect on disorders of gut-brain interaction.Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi · 2026
    Review
  8. Managing dyspepsia as a generalist.Singapore medical journal · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Editorial commentary on the Indian Journal of Gastroenterology - March-April 2021.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Siddhesh Vijay RaneDepartment of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai Central, Mumbai, 400 008, India. sid.6173@gmail.com.
Bharati AsgaonkarDepartment of Physical Therapy, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai Central, Mumbai, 400 008, India.
Pravin RathiDepartment of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai Central, Mumbai, 400 008, India.
Qais ContractorDepartment of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai Central, Mumbai, 400 008, India.
Sanjay ChandnaniDepartment of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai Central, Mumbai, 400 008, India.
Parmeshwar JunareDepartment of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai Central, Mumbai, 400 008, India.
Prasanta DebnathDepartment of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai Central, Mumbai, 400 008, India.
Vidya BhatDepartment of Physical Therapy, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai Central, Mumbai, 400 008, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional dyspepsia (FD) is a commonly encountered entity worldwide and is difficult to treat. Most of the treatment modalities have low-quality evidence for use, except for proton pump inhibitors. Aerobic exercise has been shown to improve the symptoms, but its direct effect on symptoms has never been studied. The objective was to study the effects of moderate aerobic exercise on symptoms of FD and to compare the effect of conventional treatment alone vs. exercise plus conventional treatment.

methodsOut of 112 patients, 72 were randomly divided into controls (conventional treatment; n=36) and experimental (aerobic exercise for 30 min per session, 5 times a week for 6 weeks with conventional treatment; n=36) groups. Both the groups were assessed on day 1 and at the end of 6 weeks, using Glasgow Dyspepsia Severity Score (GDSS), Depression Anxiety Stress Scales-42 (DASS-42), and visual analogue scale (VAS).

resultsPre-treatment GDSS, DASS-42, and VAS in the experimental group were significantly different as compared to the post-treatment scores (p=0.00019, p=0.0002, p=0.00019, respectively). Even in the control group, pre- and post-treatment GDSS, DASS-42, and VAS scores were significantly different (p=0.00019, p=0.0002, p=0.00019, respectively). However, on the head-to-head comparison of the 2 groups, scores at the end of 6 weeks were significantly different (p< 0.05), in favor of the experimental group.

conclusionAerobic exercise as an auxiliary therapy to conventional treatment has better outcomes in the functional well-being of dyspepsia.

Indexed as

DyspepsiaExerciseHumansProton Pump InhibitorsQuality of LifeProton Pump InhibitorsAerobic exerciseDepression Anxiety Stress Scales-42DyspepsiaEndorphinsGastrointestinal microbiomeGlasgow Dyspepsia Severity ScorePsychological stressQuality of lifeVisual analogue scale

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.