Evidence map›Paper›PMID 34037861›Full record

ArticleBasic research in cardiology2021

Translation of experimental cardioprotective capability of P2Y

Marie V Hjortbak, Kevin K W Olesen, Jacob M Seefeldt, Thomas R Lassen, Rebekka V Jensen, Alexander Perkins, Matthew Dodd, Tim Clayton, Derek Yellon, Derek J Hausenloy and 2 more

Open access · greenAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Basic research in cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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  8. Do We Really Need Aspirin Loading for STEMI?Cardiovascular drugs and therapy · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Marie V HjortbakDepartment of Clinical Medicine, Cardiology, Aarhus University, Palle Juul-Jensens Boulevard 82, 8200, Aarhus N, Denmark. hjortbak@clin.au.dk.ORCID http://orcid.org/0000-0002-3434-1394
Kevin K W OlesenDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Jacob M SeefeldtDepartment of Clinical Medicine, Cardiology, Aarhus University, Palle Juul-Jensens Boulevard 82, 8200, Aarhus N, Denmark.
Thomas R LassenDepartment of Clinical Medicine, Cardiology, Aarhus University, Palle Juul-Jensens Boulevard 82, 8200, Aarhus N, Denmark.
Rebekka V JensenDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Alexander PerkinsLondon School of Hygiene and Tropical Medicine, Clinical Trials Unit, London, UK.
Matthew DoddLondon School of Hygiene and Tropical Medicine, Clinical Trials Unit, London, UK.
Tim ClaytonLondon School of Hygiene and Tropical Medicine, Clinical Trials Unit, London, UK.
Derek YellonThe Hatter Cardiovascular Institute, University College London, London, UK.
Derek J HausenloyThe Hatter Cardiovascular Institute, University College London, London, UK.
Hans Erik BøtkerDepartment of Clinical Medicine, Cardiology, Aarhus University, Palle Juul-Jensens Boulevard 82, 8200, Aarhus N, Denmark.
CONDI-2/ERIC-PPCI investigators
Aarhus University · DKUniversity of London · GBAarhus University Hospital · DKNational University of Singapore · SGUniversity College London · GB

Funding

British Heart Foundation CS/14/3/31002British Heart Foundation FS/10/039/28270British Heart Foundation Clinical Study Grant CS/14/3/31002Danish Innovation Foundation 11-108354Danish Innovation Foundation 11-115818European Cooperation in Science and Technology CA16225Medical Research Council MC_G1002673National Medical Research Council NMRC/CGAug16C006National Medical Research Council NMRC/CSA-SI/0011/2017Novo Nordisk Fonden (DK) NNF13OC0007447
6 · The paper itself

Abstract

We studied the translational cardioprotective potential of P2Y

Indexed as

Percutaneous Coronary InterventionTranslational Research, BiomedicalAgedAnimalsBlood PlateletsClopidogrelDisease Models, AnimalFemaleHumansMaleMiddle AgedMyocardial Reperfusion InjuryPlatelet AggregationPlatelet Aggregation InhibitorsPrasugrel HydrochloridePurinergic P2Y Receptor AntagonistsClopidogrelP2ry12 protein, ratPlatelet Aggregation InhibitorsPrasugrel HydrochloridePurinergic P2Y Receptor AntagonistsReceptors, Purinergic P2Y12TicagrelorCardioprotectionIschemic conditioningMyocardial infarctionP2Y12 inhibitor

Identifiers

PMID34037861
OpenAlexW3164082427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.