Evidence map›Paper›PMID 34037850›Full record

ArticleDysphagia2022

Swallowing Safety and Efficiency Impairment Profiles in Individuals with Amyotrophic Lateral Sclerosis.

Raele Robison, Lauren DiBiase, Amy Ashley, Kasey McElheny, Amber Anderson, James P Wymer, Emily K Plowman

Open access · greenAbstract read
In one paragraph

Article in Dysphagia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Effect of respiratory training on swallowing function in swallowing disorders: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
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  11. Fiberoptic endoscopic evaluation of swallowing (FEES) in children with spinal muscular atrophy type 1: feasibility, swallowing safety and efficacy, and dysphagia phenotype.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
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  16. Acute Antipsychotic Use and Presence of Dysphagia Among Older Veterans with Heart Failure.Journal of the American Medical Directors Association · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Raele RobisonAerodigestive Research Core, University of Florida, Gainesville, FL, USA. rrobison@wisc.edu.ORCID 0000-0003-4750-0769
Lauren DiBiaseAerodigestive Research Core, University of Florida, Gainesville, FL, USA.
Amy AshleyAerodigestive Research Core, University of Florida, Gainesville, FL, USA.
Kasey McElhenyAerodigestive Research Core, University of Florida, Gainesville, FL, USA.
Amber AndersonAerodigestive Research Core, University of Florida, Gainesville, FL, USA.
James P WymerDepartment of Neurology, University of Florida, Gainesville, FL, USA.
Emily K PlowmanAerodigestive Research Core, University of Florida, Gainesville, FL, USA.
University of Florida · USUniversity of Florida Health · US

Funding

Landis Outstanding Mentor Award SupplementR01NS100859 · NINDS · UNIVERSITY OF FLORIDA · PI PLOWMAN, EMILY KATE · 2017 to 2021
$2.0M
The Role of Homeostenosis in Bulbar Function in ALS and AgingF99NS115339 · NINDS · UNIVERSITY OF FLORIDA · PI LOY, RAELE DONETHA · 2019 to 2019
$39k
NINDS NIH HHS F99 NS115339NINDS NIH HHS R01 NS100859
6 · The paper itself

Abstract

Dysphagia is common in individuals with amyotrophic lateral sclerosis (ALS) and associated with reductions in quality of life and health-related outcomes. Despite the high prevalence of dysphagia in ALS, functional impairment profiles of swallowing safety and efficiency have not been comprehensively examined. We therefore aimed to determine the relative prevalence of unsafe and inefficient swallowing in a large cohort of individuals with ALS. We further sought to examine the impact of global and bulbar disease progression (Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised "ALSFRS-R" total and bulbar scores, respectively), disease duration, and onset type on swallowing impairment profiles. One hundred individuals with ALS completed a standardized videofluoroscopic swallowing examination Two independent and blinded raters performed validated ratings of safety (Penetration-Aspiration Scale, PAS) and efficiency (Analysis of Swallowing Physiology: Events, Kinematics, and Timing, ASPEKT % residue). Binary classifications of safety (unsafe: PAS ≥ 3), efficiency (inefficient: total residue ≥ 3% of C2-4

Indexed as

Amyotrophic Lateral SclerosisDeglutition DisordersDeglutitionDisease ProgressionHumansQuality of LifeAmyotrophic lateral sclerosisDeglutitionDeglutition disordersNeurodegenerative disease

Identifiers

PMID34037850
PMCPMC8617061
OpenAlexW3164010119

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.