Evidence map›Paper›PMID 34037848›Full record

ArticleWorld journal of microbiology & biotechnology2021

Improving the catalytic efficiency and substrate affinity of a novel esterase from marine Klebsiella aerogenes by random and site-directed mutation.

Haofeng Gao, Runtao Zhu, Zelong Li, Wanyi Wang, Ziduo Liu, Nan Hu

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Targeted Mutation of a Non-catalytic Gating Residue Increases the Rate ofJournal of agricultural and food chemistry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Haofeng GaoCollege of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211800, China.
Runtao ZhuCollege of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211800, China.
Zelong LiCollege of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211800, China.
Wanyi WangCollege of Life Science and Technology, State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China.
Ziduo LiuCollege of Life Science and Technology, State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China.
Nan HuCollege of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211800, China. hunan@njut.edu.cn.ORCID http://orcid.org/0000-0002-3406-6716
Nanjing Tech University · CNHuazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel esterase (EstKa) from marine Klebsiella aerogenes was characterized with hydrolytic activity against p-nitrophenyl caprylate (pNPC, C

Indexed as

Bacterial ProteinsCaprylatesCatalysisEnterobacter aerogenesEnzyme StabilityEsterasesHydrolysisMutagenesis, Site-DirectedStructural Homology, ProteinSubstrate Specificity4-nitrophenyloctanoateBacterial ProteinsCaprylatesEsterasesEsteraseKlebsiella aerogenesRandom mutationSite-directed mutation

Identifiers

PMID34037848
OpenAlexW3165040825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.