Evidence map›Paper›PMID 34037420›Full record

ArticleJournal of virology2021

CX3CR1 Is a Receptor for Human Respiratory Syncytial Virus in Cotton Rats.

Gia Green, Sara M Johnson, Heather Costello, Kelsey Brakel, Olivia Harder, Antonius G Oomens, Mark E Peeples, Hong M Moulton, Stefan Niewiesk

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
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  6. Interplay between respiratory viruses and cilia in the airways.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Alterations in CX3CL1 Levels and Its Role in Viral Pathogenesis.International journal of molecular sciences · 2024
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Gia GreenCollege of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.
Sara M JohnsonCenter for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Heather CostelloCenter for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Kelsey BrakelCollege of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.
Olivia HarderCollege of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.
Antonius G OomensDepartment of Veterinary Pathobiology, Oklahoma State University, Stillwater, Oklahoma, USA.
Mark E PeeplesCenter for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Hong M MoultonDepartment of Biomedical Sciences, Carlson College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA.
Stefan NiewieskCollege of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.
The Ohio State University · USNationwide Children's Hospital · USOklahoma State University · USOregon State University · US

Funding

Project 3: Dr. LiP01AI112524 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI LI, JIANRONG · 2015 to 2019
$6.8M
Respiratory Syncytial Virus Targeting of the Human Airway EpitheliumR01AI093848 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI PEEPLES, MARK E. · 2012 to 2023
$3.8M
NIAID NIH HHS P01 AI112524NIAID NIH HHS R01 AI093848
6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) has been reported to use CX3CR1

Indexed as

AnimalsAntibodies, ViralBinding SitesCell LineCX3C Chemokine Receptor 1Disease Models, AnimalEpithelial CellsHeparan SulfateHumansMutationReceptors, VirusRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsRespiratory SystemSigmodontinaeViral Envelope ProteinsAntibodies, Viralattachment protein GCX3C Chemokine Receptor 1Heparan SulfateReceptors, VirusViral Envelope Proteinscotton ratCX3CR1G proteinreceptorrespiratory syncytial virus

Identifiers

PMID34037420
PMCPMC8312862
OpenAlexW3165147088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.