Evidence map›Paper›PMID 34037223›Full record

ArticleInflammatory bowel diseases2022

Increasing Prevalence and Stable Incidence Rates of Inflammatory Bowel Disease Among First Nations: Population-Based Evidence From a Western Canadian Province.

Juan Nicolás Peña-Sánchez, Jessica Amankwah Osei, Jose Diego Marques Santos, Derek Jennings, Mustafa Andkhoie, Colten Brass, Germain Bukassa-Kazadi, Xinya Lu, Michelle Johnson-Jennings, Linda Porter and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Inflammatory bowel diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Cross-national comparison of inflammatory bowel disease burden in China, Japan, the United States, and India: An age-period-cohort analysis of GBD 2021.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Article
  4. Review
  5. Assessing colorectal cancer screening and outcomes among First Nations people in Alberta.Journal of the Canadian Association of Gastroenterology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Patient and Public Involvement in Inflammatory Bowel Disease Research-A Scoping Review.Journal of the Canadian Association of Gastroenterology · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The 2023 Impact of Inflammatory Bowel Disease in Canada: Epidemiology of IBD.Journal of the Canadian Association of Gastroenterology · 2023
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Juan Nicolás Peña-SánchezDepartment of Community Health and Epidemiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID 0000-0002-4653-525X
Jessica Amankwah OseiDepartment of Community Health and Epidemiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID 0000-0002-5773-609X
Jose Diego Marques SantosDepartment of Community Health and Epidemiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID 0000-0001-7973-7678
Derek JenningsDepartment of Community Health and Epidemiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Mustafa AndkhoieSchool of Public Health, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID 0000-0002-6600-0797
Colten BrassMuskoday First Nation, Saskatchewan, Canada.
Germain Bukassa-KazadiHealth Surveillance and Assessment Unit Service, Department of Indigenous Services Canada, Regina, Saskatchewan, Canada.
Xinya LuSaskatchewan Health Quality Council, Saskatoon, Saskatchewan, Canada.
Michelle Johnson-JenningsDepartment of Indigenous Studies, College of Arts and Science, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID 0000-0002-0140-407X
Linda PorterOne Arrow First Nation, Saskatchewan, Canada.
Rob PorterYork Factory First Nation, Manitoba, Canada.
Carol-Lynne QuintinCrohn's and Colitis Canada, Saskatchewan Chapter, Saskatoon, Saskatchewan, Canada.
Rhonda SandersonJames Smith Cree Nation, Saskatchewan,Canada.
Ulrich TeucherDepartment of Psychology, College of Arts and Science, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Sharyle FowlerDivision of Gastroenterology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID 0000-0002-2721-1591
University of Saskatchewan · CACrohn's and Colitis Canada · CASaskatchewan Health · CASaskatchewan Health Quality Council · CA

Funding

NIMHD NIH HHS L32 MD007420
6 · The paper itself

Abstract

backgroundThere is limited to no evidence of the prevalence and incidence rates of inflammatory bowel disease (IBD) among Indigenous peoples. In partnership with Indigenous patients and family advocates, we aimed to estimate the prevalence, incidence, and trends over time of IBD among First Nations (FNs) since 1999 in the Western Canadian province of Saskatchewan.

methodsWe conducted a retrospective population-based study linking provincial administrative health data from the 1999-2000 to 2016-2017 fiscal years. An IBD case definition requiring multiple health care contacts was used. The prevalence and incidence data were modeled using generalized linear models and a negative binomial distribution. Models considered the effect of age groups, sex, diagnosis type (ulcerative colitis [UC], Crohn disease [CD]), and fiscal years to estimate prevalence and incidence rates and trends over time.

resultsThe prevalence of IBD among FNs increased from 64/100,000 (95% confidence interval [CI], 62-66) in 1999-2000 to 142/100,000 (95% CI, 140-144) people in 2016-2017, with an annual average increase of 4.2% (95% CI, 3.2%-5.2%). Similarly, the prevalence of UC and CD, respectively, increased by 3.4% (95% CI, 2.3%-4.6%) and 4.1% (95% CI, 3.3%-4.9%) per year. In contrast, the incidence rates of IBD, UC, and CD among FNs depicted stable trends over time; no statistically significant changes were observed in the annual change trend tests. The ratio of UC to CD was 1.71.

conclusionsWe provided population-based evidence of the increasing prevalence and stable incidence rates of IBD among FNs. Further studies are needed in other regions to continue understanding the patterns of IBD among Indigenous peoples.

Indexed as

Inflammatory Bowel DiseasesCanadaHumansIncidencePrevalenceRetrospective StudiesCrohn diseaseepidemiologyIndigenous peopleinflammatory bowel diseasepopulation groupulcerative colitis

Identifiers

PMID34037223
PMCPMC8972279
OpenAlexW3165142975

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.