ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2022
New criteria for the diagnosis of infective endocarditis using 18F-FDG PET/CT imaging.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Multiple Imaging Modalities in the Diagnosis of Infective Endocarditis.Reviews in cardiovascular medicine · 2025Review
- New semiquantitative parameters in digital [EJNMMI reports · 2025Article
- Diagnostic Utility ofMicroorganisms · 2025Article
- Dual-Time-Point 18F-FDG PET/CT in Infective Endocarditis: Impact of Delayed Imaging in the Definitive Diagnosis of Endocarditis.Biomedicines · 2024Article
- Multimodality Imaging Diagnosis in Infective Endocarditis.Life (Basel, Switzerland) · 2023Review
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2022: positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- Advances in Molecular Imaging in Infective Endocarditis.Vaccines · 2023Review
- Response to JNC-22-024-LE.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- New criteria to diagnose infective endocarditis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- FDG PET/CT in Cardiac Infection: Does It Matter? A Narrative Review.Infectious diseases and therapy · 2022Review
- FDG PET in infective endocarditis: There are still horizons to conquer.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Article
- Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe purpose of this study was to examine a qualitative scoring system and a semi-quantitative method of FDG-PET/CT imaging in the diagnosis of infective endocarditis (IE).
methodsWe retrospectively included 108 patients who underwent 18F-FDG-PET/CT for suspected IE. PET/CT scans were interpreted using a 4-point score (0 = no uptake; 1 = cardiac uptake < blood-pool activity; 2 = blood-pool < uptake < liver activity; 3 = uptake > liver) and semi-quantitatively using SUVmax and SUVmean of the suspected valve lesion, liver, spleen, and of the bone marrow (BM). BM and spleen SUVmean were normalized to the liver, and hypermetabolism (HSBM) was defined as a BM or spleen-to-liver ratio > 1.
resultsComparing the score criteria results with the clinical final diagnosis, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of qualitative criteria were 93%, 81%, 84%, 91%, and 87%, respectively. A definite IE was documented in 83% of patients showing HSBM and abnormal cardiac uptake, 44% with abnormal cardiac uptake, 28% with HSBM, and 10% with neither one.
conclusionThe qualitative scoring system is helpful in the diagnosis of IE. The HSBM is an additional, reliable indirect sign of IE.
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