SynthesisAIDS and behavior2021
Changing Knowledge and Attitudes Towards HIV Treatment-as-Prevention and "Undetectable = Untransmittable": A Systematic Review.
Synthesis in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Undetectable = Untransmittable: A Cross-Population Systematic Review and Meta-Analysis on Awareness and Acceptance.Pathogens (Basel, Switzerland) · 2025Pooled it
- Integrating 'undetectable equals untransmittable' into HIV counselling in South Africa: the development of locally acceptable communication tools using intervention mapping.BMC public health · 2024Pooled it
- The long-term impact of family economic empowerment on viral suppression and mental health outcomes among adolescents living with HIV in low-income settings: A cluster-randomized controlled trial in Southern Uganda.Social science & medicine (1982) · 2025Trial
- Impact of SMS and peer navigation on retention in HIV care among adults in South Africa: results of a three-arm cluster randomized controlled trial.Journal of the International AIDS Society · 2021Trial
- Disentangling Between- and Within-Person Effects of HIV PrEP and Treatment Attitudes on Condom Use and Bacterial STIs Among Sexual Minority Men.AIDS and behavior · 2026Article
- Digitally Adapting LGBTQ-Affirmative Cognitive Behavioral Therapy for Chinese Men Who Have Sex With Men Living With HIV: User-Centered Design Approach.Journal of medical Internet research · 2026Article
- The Cost and Intermediate Cost-Effectiveness of a Randomized Control Trial Delivering U=U Messaging to Increase HIV Testing Among South African Men.Global health, science and practice · 2026Article
- Durability of HIV viral suppression in South Africa: a national cohort study.The lancet. HIV · 2026Observational
- U = U for all: Advancing equity in HIV prevention.PLoS medicine · 2026Article
- Narratives of Disconnection: A Life Course Perspective of Methamphetamine Use Among Sexual Minority Men Living with HIV.International journal of behavioral medicine · 2026Article
- A Novel 8 Ps Framework for Addressing Complexities in Sexual Health Histories for US Healthcare Providers.Perspectives on sexual and reproductive health · 2025Article
- A call to action to advance global research priorities related to Undetectable = Untransmittable.Journal of the International AIDS Society · 2025Article
- Suboptimal Patient-Provider Communication About Undetectable = Untransmittable and HIV Transmission Risk in Australia and the US.AIDS and behavior · 2025Article
- Article
- MINMON-J: a hybrid implementation pilot study evaluating a low-barrier hepatitis C treatment model in a jail setting.BMJ open · 2025Article
- Should Digital Interventions for HIV Self-Testing Be Regulated with World Health Organization Prequalification?JMIR mHealth and uHealth · 2025Article
- Experiences of undetectable = untransmittable among couples with different HIV serostatus: a qualitative study in Tanzania and Uganda.BMC public health · 2025Article
- Identifying Health Care Services Offered in the HIV Care Continuum via a Machine Learning-Based Topic Modeling Approach: Exploratory Literature Review.JMIR public health and surveillance · 2025Review
- Knowledge and stigma of people living with HIV treated in a medication dispensing unit: a cross-sectional study.BMC public health · 2025Article
- The Implications of HIV Biomedical Prevention for Perceived HIV Risk and Psychosexual Health among Sexual Minority Men in the United States.Archives of sexual behavior · 2025Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
People on HIV treatment with undetectable virus cannot transmit HIV sexually (Undetectable = Untransmittable, U = U). However, the science of treatment-as-prevention (TasP) may not be widely understood by people with and without HIV who could benefit from this information. We systematically reviewed the global literature on knowledge and attitudes related to TasP and interventions providing TasP or U = U information. We included studies of providers, patients, and communities from all regions of the world, published 2008-2020. We screened 885 papers and abstracts and identified 72 for inclusion. Studies in high-income settings reported high awareness of TasP but gaps in knowledge about the likelihood of transmission with undetectable HIV. Greater knowledge was associated with more positive attitudes towards TasP. Extant literature shows low awareness of TasP in Africa where 2 in 3 people with HIV live. The emerging evidence on interventions delivering information on TasP suggests beneficial impacts on knowledge, stigma, HIV testing, and viral suppression.Review was pre-registered at PROSPERO: CRD42020153725.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.