Evidence map›Paper›PMID 34036407›Full record

ReviewLangenbeck's archives of surgery2021

Functional syndromes and symptom-orientated aftercare after esophagectomy.

Kristjan Ukegjini, Diana Vetter, Rebecca Fehr, Valerian Dirr, Christoph Gubler, Christian A Gutschow

Abstract readReview
In one paragraph

Review in Langenbeck's archives of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Revisional surgery for delayed gastric conduit emptying after esophagectomy: the RESTORANT project.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2026
    Article
  5. Influence of dietary intake and eating patterns on reactive hypoglycemic events in patients postesophagectomy: A prospective observational study using continuous glucose monitoring.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Observational
  6. Article
  7. Trajectories of postoperative nutritional risk changes in patients with oesophageal cancer and their relationship with symptom recovery-a multicentre longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  8. Article
  9. Review
  10. Delayed gastric conduit emptying after esophagectomy: attempt at a clinically relevant classification.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Mixed Esophageal Disease (MED): A New Concept.Digestive diseases and sciences · 2023
    Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kristjan UkegjiniDepartment of Visceral and Transplant Surgery, University Hospital Zurich, Zurich, Switzerland.
Diana VetterDepartment of Visceral and Transplant Surgery, University Hospital Zurich, Zurich, Switzerland.
Rebecca FehrDepartment of Endocrinology, Diabetology and Clinical Nutrition, University Hospital Zurich, Zurich, Switzerland.
Valerian DirrDepartment of Visceral and Transplant Surgery, University Hospital Zurich, Zurich, Switzerland.
Christoph GublerDepartment of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland.
Christian A GutschowDepartment of Visceral and Transplant Surgery, University Hospital Zurich, Zurich, Switzerland. christian.gutschow@usz.ch.ORCID http://orcid.org/0000-0001-6171-4427

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgery is the cornerstone of esophageal cancer treatment but remains burdened with significant postoperative changes of gastrointestinal function and quality of life. PURPOSE: The aim of this narrative review is to assess and summarize the current knowledge on postoperative functional syndromes and quality of life after esophagectomy for cancer, and to provide orientation for the reader in the challenging field of functional aftercare.

conclusionsPost-esophagectomy syndromes include various conditions such as dysphagia, reflux, delayed gastric emptying, dumping syndrome, weight loss, and chronic diarrhea. Clinical pictures and individual expressions are highly variable and may be extremely distressing for those affected. Therefore, in addition to a mostly well-coordinated oncological follow-up, we strongly emphasize the need for regular monitoring of physical well-being and gastrointestinal function. The prerequisite for an effective functional aftercare covering the whole spectrum of postoperative syndromes is a comprehensive knowledge of the pathophysiological background. As functional conditions often require a complex diagnostic workup and long-term therapy, close interdisciplinary cooperation with radiologists, gastroenterologists, oncologists, and specialized nutritional counseling is imperative for successful management.

Indexed as

Esophageal NeoplasmsEsophagectomyAftercareDumping SyndromeHumansPostoperative ComplicationsQuality of LifeDelayed gastric emptyingDumping syndromeDysphagiaEsophagectomyFunctional aftercareFunctional syndromesQuality of life

Identifiers

PMID34036407
PMCPMC8578083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.