Evidence map›Paper›PMID 34036276›Full record

ArticleCritical care explorations2021

A Multicenter Evaluation of Survival After In-Hospital Cardiac Arrest in Coronavirus Disease 2019 Patients.

Abhishek Bhardwaj, Mahmoud Alwakeel, Talha Saleem, Saira Afzal, Sura Alqaisi, Aisha R Saand, Hanan Al Najjar, Lori Griffiths, Xiaozhen Han, Xiaofeng Wang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Abhishek BhardwajDepartment of Pulmonary and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH.
Mahmoud AlwakeelDepartment of Internal Medicine, Cleveland Clinic Fairview Hospital, Cleveland, OH.
Talha SaleemDepartment of Internal Medicine, Cleveland Clinic Fairview Hospital, Cleveland, OH.
Saira AfzalDepartment of Internal Medicine, Cleveland Clinic Fairview Hospital, Cleveland, OH.
Sura AlqaisiDepartment of Internal Medicine, Cleveland Clinic Fairview Hospital, Cleveland, OH.
Aisha R SaandDepartment of Internal Medicine, Cleveland Clinic Fairview Hospital, Cleveland, OH.
Hanan Al NajjarDepartment of Internal Medicine, Cleveland Clinic Fairview Hospital, Cleveland, OH.
Lori GriffithsDepartment of Quality Data Registries, Cleveland Clinic, Cleveland, OH.
Xiaozhen HanDepartment of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.
Xiaofeng WangDepartment of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.
Silvia Perez-ProttoDepartments of Outcomes Research and Intensive Care and Resuscitation, Anesthesiology Institute, Cleveland Clinic, Cleveland, OH.
Benjamin S AbellaDepartment of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA.
David F GaieskiCleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
Abhijit DuggalDepartment of Pulmonary and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH.
Francois Abi FadelDepartment of Pulmonary and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH.
Cleveland Clinic · USCleveland Clinic Lerner College of Medicine · USThomas Jefferson University · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceIn-hospital cardiac arrest survival among coronavirus disease 2019 patients has been reported to range from 0% to 12%. These numbers are significantly lower than reported prepandemic in-hospital cardiac arrest survival rates of approximately 20-25% in the United States for non-coronavirus disease 2019 patients.

objectiveTo assess the incidence of in-hospital cardiac arrest survival of coronavirus disease 2019 patients.

designA retrospective cohort study of adult patients with coronavirus disease 2019 subsequently found to have in-hospital cardiac arrest and underwent cardiopulmonary resuscitation (cardiopulmonary resuscitation).

settingMultiple hospitals of the Cleveland Clinic Health System. PATIENTS: All adult patients (age ≥ 18 yr) admitted to Cleveland Clinic Health System with a diagnosis of coronavirus disease 2019 who experienced in-hospital cardiac arrest requiring cardiopulmonary resuscitation. MEASUREMENTS AND MAIN

resultsFrom March 01, 2020 to October 15, 2020, 3,555 patients with coronavirus disease 2019 were hospitalized; 1,372 were admitted to the ICU; 58 patients had in-hospital cardiac arrest. Median age of this cohort was 66.5 years (interquartile range, 55.0-76.0 yr). Patients were predominantly male (62.5%), White (53.4%), with a median body mass index of 29.7 (interquartile range, 25.8-34.6). Most in-hospital cardiac arrests were in critical care environments (ICU), 51 of 58 (87.9%); seven of 58 (12.1%) were on ward locations. Thirty-four of 58 patients (58.6%) were on mechanical ventilation prior to in-hospital cardiac arrest with a median duration of mechanical ventilation of 9 days (interquartile range, 2-18 d). Twenty-four of 58 patients (44%) were on vasopressors prior to arrest. Initial arrest rhythm was pulseless electrical activity at (63.8%), asystole (29.3%), and pulseless ventricular tachycardia/fibrillation (6.9%). Of the 58 patients, 35 (60.3%) attained return of spontaneous circulation, and 13 of 58 (22.4%) were discharged alive.

conclusionsWe report a 22% survival to discharge after in-hospital cardiac arrest in coronavirus disease 2019 patients, a survival rate similar to before the coronavirus disease 2019 pandemic.

Indexed as

cardiac arrestcardiopulmonary resuscitationcoronavirus disease 2019resuscitationsevere acute respiratory syndrome coronavirus 2survivorship

Identifiers

PMID34036276
PMCPMC8133239
OpenAlexW3162625173

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.