ArticlePlastic and reconstructive surgery. Global open2021
Chronic Nerve Injuries and Delays in Surgical Treatment Negatively Impact Patient-reported Quality of Life.
Article in Plastic and reconstructive surgery. Global open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Insights into the Effects of Carbamylated Erythropoietin on Schwann Cells in Peripheral Nerve Injury.International journal of molecular sciences · 2026Article
- A novel platelet-rich plasma clinically induces reliable, rapid, long-term chronic peripheral neuropathic pain elimination.Experimental biology and medicine (Maywood, N.J.) · 2026Article
- Opiorphin and neuropathic pain: a promising treatment approach?Inflammopharmacology · 2025Review
- Analysis of Penetrating Injuries to the Sciatic Nerve, Highlighting Insights From Sudan.Plastic and reconstructive surgery. Global open · 2025Article
- Assessment, management, and rehabilitation of traumatic peripheral nerve injuries for non-surgeons.Muscle & nerve · 2025Review
- An emulsion electrospun nanofibrous scaffold loaded with glial cell line-derived neurotrophic factor for nerve regeneration.Frontiers in cell and developmental biology · 2025Article
- Quantitative evaluation of rat sciatic nerve degeneration using high-frequency ultrasound.Scientific reports · 2023Article
- Patient reported symptoms and disabilities before and after neuroma surgery: a register-based study.Scientific reports · 2023Article
- Serum neurofilament light chain measurements following nerve trauma.Journal of the peripheral nervous system : JPNS · 2023Article
- Surgical Technique for Targeted Muscle Reinnervation in Knee Disarticulation Amputation for Nonambulatory Patients.Plastic and reconstructive surgery. Global open · 2023Article
- Pronator Quadratus: A Preferable Recipient for Targeted Muscle Reinnervation of Neuromas in the Hand.Plastic and reconstructive surgery. Global open · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
Little emphasis has been paid to characterize quality of life (QoL) burdens experienced by patients seeking surgical treatment for nerve injuries and neuropathic pain.
methodsA cross-sectional survey was distributed to all patients (N = 767) from a single nerve surgeon's practice between 2014 and 2019. Data collected included demographics, specifics of the injury and symptoms, time to referral, and effects of the injury, surgery, and timing of surgery on QoL.
resultsOf the 767 patients, 209 (27.2%) completed the survey. Average age was 48.8 years; 68.9% of patients were women and 31.1% men. At presentation, 68% had experienced symptoms for more than 1 year; 86.1% reported severity as being profound; 97.6% reported QoL was at least moderately negatively impacted by nerve injury; 70% felt they should have been referred earlier for surgical evaluation; 51.2% were not told that nerve surgery was an option for their problem; 83.1% felt that earlier referral would have improved their QoL. After surgery, symptoms were significantly mitigated in 55.5% of the patients, moderately mitigated in 21.5%. Patients reported QoL was significantly (59.8%) or at least moderately (76.6%) improved by nerve surgery.
conclusionsThe majority of patients reported that nerve injuries imparted a moderate to severe impact on QoL, and that surgical treatment improved QoL. Most patients felt that earlier referral for surgical intervention would have led to better outcome and positively impacted QoL. Interdisciplinary treatment algorithms, including a role for surgical intervention, may be helpful in facilitating timely diagnosis, referral, and thus improved outcomes.
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