Evidence map›Paper›PMID 34035973›Full record

ArticleJournal of analytical methods in chemistry2021

Development of Simple Analytical Method for B-Group Vitamins in Nutritional Products: Enzymatic Digestion and UPLC-MS/MS Quantification.

Quang Huy Nguyen, Anh Quoc Hoang, Thi My Hanh Truong, Thi Diu Dinh, Thi Thuy Le, Thi Huyen Trang Luu, Viet Chien Dinh, Thi Minh Thu Nguyen, Thi Trang Vu, Thi Anh Huong Nguyen

Abstract read
In one paragraph

Article in Journal of analytical methods in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Direct parallel electrosynthesis of high-value chemicals from atmospheric components on symmetry-breaking indium sites.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Quang Huy NguyenFaculty of Chemistry, University of Science, Vietnam National University, 19 Le Thanh Tong, Hanoi 10000, Vietnam.
Anh Quoc HoangFaculty of Chemistry, University of Science, Vietnam National University, 19 Le Thanh Tong, Hanoi 10000, Vietnam.
Thi My Hanh TruongFaculty of Chemistry, University of Science, Vietnam National University, 19 Le Thanh Tong, Hanoi 10000, Vietnam.
Thi Diu DinhFaculty of Chemistry, University of Science, Vietnam National University, 19 Le Thanh Tong, Hanoi 10000, Vietnam.
Thi Thuy LeNational Institute for Food Control (NIFC), 65 Pham Than Duat, Hanoi 10000, Vietnam.
Thi Huyen Trang LuuNational Institute for Food Control (NIFC), 65 Pham Than Duat, Hanoi 10000, Vietnam.
Viet Chien DinhNational Institute for Food Control (NIFC), 65 Pham Than Duat, Hanoi 10000, Vietnam.ORCID https://orcid.org/0000-0002-6168-4560
Thi Minh Thu NguyenFaculty of Chemistry, University of Science, Vietnam National University, 19 Le Thanh Tong, Hanoi 10000, Vietnam.ORCID https://orcid.org/0000-0002-6982-8071
Thi Trang VuNational Institute for Food Control (NIFC), 65 Pham Than Duat, Hanoi 10000, Vietnam.ORCID https://orcid.org/0000-0003-0924-6376
Thi Anh Huong NguyenFaculty of Chemistry, University of Science, Vietnam National University, 19 Le Thanh Tong, Hanoi 10000, Vietnam.ORCID https://orcid.org/0000-0003-1047-9548

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A method for the simultaneous determination of seven B-group vitamers including thiamine, riboflavin, nicotinamide, niacin, pyridoxine, pyridoxal, and pyridoxamine in nutritional products by using enzymatic digestion followed by LC-MS/MS quantification was studied. The LC-MS/MS conditions such as MS transitions, mobile phase programs, and ammonium formate buffer concentrations, and sample treatment procedures (e.g., concentrations of buffer solution, digestion temperature, and digestion time) were investigated. The analytical method performance was evaluated by multiple criteria such as selectivity, linearity, detection and quantification limits, repeatability, reproducibility, and recovery by using real sample matrices. The validated method was successfully applied to analyze vitamin B concentrations in different nutritional products like ultra-heat-treated milk, powdered milk, and nutritional powder. Vitamin B concentrations varied over a wide range from lower than detection limits to about 9000

Identifiers

PMID34035973
PMCPMC8116160

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.