Evidence map›Paper›PMID 34035853›Full record

ReviewExperimental and therapeutic medicine2021

COVID-19-related thyroid conditions (Review).

Florica Șandru, Mara Carsote, Răzvan Cosmin Petca, Ancuta Augustina Gheorghisan-Galateanu, Aida Petca, Ana Valea, Mihai Cristian Dumitrașcu

Open access · diamondAbstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Are Thyroid Functions Affected in Multisystem Inflammatory Syndrome in Children?Journal of clinical research in pediatric endocrinology · 2022
    Article
  5. Article
  6. Post-COVID-19 Condition: Where Are We Now?Life (Basel, Switzerland) · 2022
    Review
  7. Hypothyroidism and Subclinical Hypothyroidism as a Consequence of COVID-19 Infection.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Florica ȘandruDepartment of Dermatology, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Mara CarsoteDepartment of Endocrinology, 'C. I. Parhon' National Institute of Endocrinology, 011863 Bucharest, Romania.
Răzvan Cosmin PetcaDepartament of Urology, 'Carol Davila' University of Medicine and Pharmacy, 050474, Bucharest, Romania.
Ancuta Augustina Gheorghisan-GalateanuDepartment of Endocrinology, 'C. I. Parhon' National Institute of Endocrinology, 011863 Bucharest, Romania.
Aida PetcaDepartment of Obstetrics and Gynecology, 'Elias' Emergency University Hospital, 011461 Bucharest, Romania.
Ana ValeaEndocrinology Department, Clinical County Hospital, 400000 Cluj-Napoca, Romania.
Mihai Cristian DumitrașcuDepartament of Obstetrics and Gynecology, 'Carol Davila' University of Medicine and Pharmacy, 050474, Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROInstitutul Național de Endocrinologie C.I. Parhon · ROEmergency University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients who were not previously diagnosed with any thyroid conditions, the scenario of COVID-19-related anomalies of the hypothalamus-pituitary-thyroid axes may include either: A process of central thyroid stimulating hormone (TSH) disturbances via virus-related hypophysitis; an atypical type of subacute thyroiditis which is connected to the virus spread or to excessive cytokine production including a destructive process with irreversible damage of the gland or low T3 (triiodothyronine) syndrome (so called non-thyroid illness syndrome) which is not specifically related to the COVID-19 infection, but which is associated with a very severe illness status. Our objective here was to briefly review thyroid changes due to the COVID-19 infection. Ongoing assessment of the effects of the COVID-19 pandemic will reveal more information on coronavirus-induced thyroid conditions. Routine thyroid assays performed in patients with severe infection/at acute phase of COVID-19 are encouraged in order to detect thyrotoxicosis. After recovery, thyroid function should be assessed to identify potential hypothyroidism. There remain unanswered questions related to the prognostic value of interleukin-6 in infected patients, especially in cases with cytokine storm, and the necessity of thyroid hormone replacement in subjects with hypophysitis-related central hypothyroidism.

Indexed as

COVID-19interleukin-6thyroidthyroiditisthyrotoxicosis

Identifiers

PMID34035853
PMCPMC8135141
OpenAlexW3160425484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.