ArticleGastroenterology & hepatology2020
Diagnosis and Management of Esophagogastric Junction Outflow Obstruction.
Article in Gastroenterology & hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility.United European gastroenterology journal · 2025Guideline
- Timed Barium Esophagography in Esophagogastric Junction Outflow Obstruction: A Retrospective Radiologic Assessment.Diagnostics (Basel, Switzerland) · 2026Article
- Article
- A Pilot Study of Corticosteroid Treatment for Achalasia-Variant Esophagogastric Junction Outflow Obstruction.Gastro hep advances · 2026Review
- Functional Lumen Imaging Probe Measurement Post-Pneumatic Dilation in Clinically Relevant Esophagogastric Junction Outlet Obstruction.Neurogastroenterology and motility · 2025Article
- Obesity Impacts the Likelihood of Symptom Resolution in Patients with Esophagogastric Junction Outflow Obstruction.Dysphagia · 2025Article
- Esophageal Per-Oral Endoscopic Myotomy (E-POEM): Future Directions and Perspectives.Current gastroenterology reports · 2024Review
- Esophagogastric Junction Outflow Obstruction (EGJOO): A Manometric Phenomenon or Clinically Impactful Problem.Current gastroenterology reports · 2024Review
- Artificial Intelligence Tools for Improving Manometric Diagnosis of Esophageal Dysmotility.Current gastroenterology reports · 2024Review
- Look above the IRP: predicting abnormal confirmatory testing in patients with esophagogastric junction outflow obstruction.Therapeutic advances in gastroenterology · 2024Article
- Peroral Endoscopic Myotomy (POEM) and Laparoscopic Heller Myotomy with Dor Fundoplication for Esophagogastric Junction Outflow Obstruction (EGJOO): a Comparison of Outcomes and Impact on Physiology.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- Oesophageal stasis is a risk factor for chronic lung allograft dysfunction and allograft failure in lung transplant recipients.ERJ open research · 2023Article
- Major mixed motility disorders: An important subset of esophagogastric junction outflow obstruction.Neurogastroenterology and motility · 2023Review
- Esophageal Motility Disorders: Current Approach to Diagnostics and Therapeutics.Gastroenterology · 2022Review
- Can FLIP guide therapy in idiopathic esophagogastric junction outflow obstruction?Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2022Article
- The effects of different postures and provocative swallow materials on the normative Chicago 3.0 metrics in a healthy Asian population.Journal of gastroenterology and hepatology · 2021Article
- Diagnostic approach to patients with suspected motility disorders: one size does not fit all.Annals of gastroenterologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Esophagogastric junction outflow obstruction (EGJOO) is an abnormal topographic pattern seen on high-resolution manometry. EGJOO is characterized by an elevated median integrated relaxation pressure with intact or weak peristalsis, thus not meeting the criteria for achalasia. This diagnosis has a female predominance and is associated with varying presenting symptoms. EGJOO can be idiopathic or secondary. It is important to assess for secondary causes, including structural or medication-related ones. Cross-sectional imaging is recommended to rule out secondary causes; however, increasing evidence suggests that esophagogastroduodenoscopy and barium esophagram are usually sufficient. The disease course is variable, with up to three-quarters of patients experiencing spontaneous resolution of symptoms over 6 months. In patients who have mild symptoms, it is reasonable to observe and consider treatment if symptoms persist. Variable response has been seen in small studies with both medical treatment and botulinum toxin injection of the lower esophageal sphincter. For patients with significant symptoms and objective evidence of obstruction on imaging, targeted therapy of the lower esophageal sphincter should be considered via pneumatic dilation or myotomy.
Indexed as
Identifiers
34035712PMC8132699What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.