Evidence map›Paper›PMID 34035663›Full record

ReviewCanada communicable disease report = Releve des maladies transmissibles au Canada2021

Practical guidance for clinical laboratories for SARS-CoV-2 serology testing.

Carmen Charlton, Jamil Kanji, Vanessa Tran, Julianne Kus, Jonathan Gubbay, Carla Osiowy, Jason Robinson, Inna Sekirov, Michael Drebot, Todd Hatchette and 11 more

Abstract readReview
In one paragraph

Review in Canada communicable disease report = Releve des maladies transmissibles au Canada, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Evaluation of the performance of multiple immunoassay diagnostic platforms on the National Microbiology Laboratory SARS-CoV-2 National Serology Panel.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2022
    Article
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Carmen CharltonPublic Health Laboratory, Alberta Precision Laboratories, Edmonton, AB.
Jamil KanjiPublic Health Laboratory, Alberta Precision Laboratories, Edmonton, AB.
Vanessa TranPublic Health Ontario Laboratory, Toronto, ON.
Julianne KusPublic Health Ontario Laboratory, Toronto, ON.
Jonathan GubbayPublic Health Ontario Laboratory, Toronto, ON.
Carla OsiowyNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB.
Jason RobinsonProvincial Laboratory Services, Division of Clinical Chemistry, Health PEI, Charlottetown, PE.
Inna SekirovBritish Columbia Centre for Disease Control Public Health Laboratory, Vancouver, BC.
Michael DrebotNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB.
Todd HatchetteNewfoundland and Labrador Public Health Microbiology Laboratory, St. John's, NL.
Derek SteinDepartment of Medical Microbiology and Infectious Disease, University of Manitoba, Winnipeg, MB.
Nadia El-GabalawyNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB.
Amanda LangRoy Romanow Provincial Laboratory, Regina, SK.
Lei JiaoNewfoundland and Labrador Public Health Microbiology Laboratory, St. John's, NL.
Paul LevettDepartment of Medical Microbiology and Infectious Disease, University of Manitoba, Winnipeg, MB.
Heidi WoodNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB.
Christian TherrienLaboratoire de santé publique du Québec, Institut national de santé publique du Québec, Sainte-Anne-de-Bellevue, QC.
L Robbin LindsayNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB.
Muhammad MorshedBritish Columbia Centre for Disease Control Public Health Laboratory, Vancouver, BC.
Jessica ForbesDepartment of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON.
Antonia DibernardoNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The landscape of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic testing is rapidly evolving. While serology testing has limited diagnostic capacity for acute infection, its role in providing population-based information on positivity rates and informing evidence-based decision making for public health recommendations is increasing. With the global availability of vaccines, there is increasing pressure on clinical laboratories to provide antibody screening and result interpretation for vaccinated and non-vaccinated individuals. Here we present the most up-to-date data on SARS-CoV-2 antibody timelines, including the longevity of antibodies, and the production and detection of neutralizing antibodies. Additionally, we provide practical guidance for clinical microbiology laboratories to both verify commercial serology assays and choose appropriate testing algorithms for their local populations.

Indexed as

COVID-19SARS-CoV-2serological testingserology algorithms

Identifiers

PMID34035663
PMCPMC8127682

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.