Evidence map›Paper›PMID 34035520›Full record

ArticleNature chemical biology2021

A new phase for enzyme kinetics.

Brian G O'Flynn, Tanja Mittag

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Phase separation of DDHD2 remodels lipid metabolism to dictate treatment sensitivity in luminal breast cancer.Proceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Brian G O'FlynnDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Tanja MittagDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA. tanja.mittag@stjude.org.ORCID http://orcid.org/0000-0002-1827-3811

Funding

The role of weak multivalent interactions and phase separation in SPOP tumor suppressor functionR01GM112846 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI MITTAG, TANJA · 2015 to 2023
$3.0M
NIGMS NIH HHS R01 GM112846
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Kinetics

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.