ReviewEye (London, England)2021
Biocompatibility of intraocular liquid tamponade agents: an update.
Review in Eye (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 40 citations in OpenAlex.
- Combined Light-Heavy Silicone Oil Endotamponade Compared with Heavy or Light Silicone Oil Endotamponade for Complex Rhegmatogenous Retinal Detachment: A Randomized Controlled Trial.Ophthalmology and therapy · 2026Article
- Complications of silicone oil in vitreoretinal surgery: a narrative review of clinical and experimental evidence.International journal of retina and vitreous · 2026Review
- Next-generation smart ophthalmic biomaterials: From passive response to active interaction and closed-loop control.Bioactive materials · 2026Review
- Influence of drainage retinotomy on anatomical and visual outcomes of pars plana vitrectomy for primary rhegmatogenous retinal detachment.BMJ open ophthalmology · 2025Article
- Ultrasound biomicroscopy assessment of the subclinical involvement of the aqueous drainage structures after silicone oil tamponade.International ophthalmology · 2025Observational
- Safety profile of lutein-based blue dyes and surgical lights.Frontiers in pharmacology · 2025Article
- The Role of Eye Movements in the Process of Silicone Oil Emulsification After Vitreoretinal Surgery.Bioengineering (Basel, Switzerland) · 2024Article
- Efficacy of Foldable Capsular Vitreous Body Implants Filled With Light or Heavy Silicone Oil in the Treatment of Silicone Oil-dependent Eyes.Translational vision science & technology · 2024Article
- Updates on Treatment Modalities for Primary Rhegmatogenous Retinal Detachment Repair.Diagnostics (Basel, Switzerland) · 2024Review
- Refinements in the use of silicone oil as an intraocular tamponade.Eye (London, England) · 2024Review
- A minimum specification dataset for liquid ocular endotamponades: recommendations by a European expert panel.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Unexplained visual loss in retinal detachment repair: comparing gas, silicone oil and heavy silicone oil by multivariable regression.International journal of retina and vitreous · 2023Article
- Safety Profile of Lutein- Versus Triamcinolone Acetonide-Based Vitreous Staining.Translational vision science & technology · 2023Article
- Subepithelial white deposition in the cornea associated with silicone oil and surgical management: a case report.Frontiers in medicine · 2023Article
- Editorial: Imaging in Ophthalmology.Journal of clinical medicine · 2022Article
- Retinal and Corneal Changes Associated with Intraocular Silicone Oil Tamponade.Journal of clinical medicine · 2022Review
- Silicone Oil Migration into the Graft Interface after Descemet Stripping Automated Endothelial Keratoplasty in a Patient with a Past Surgical History of Silicone Oil Tamponade: A Case Report.Case reports in ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intraocular liquids tamponade agents, such as perfluorocarbon liquids (PFCLs), semifluorinated alkanes (SFAs), silicone oils (SOs) and heavy silicone oils (HSOs), are a crucial intraoperative and/or postoperative tool in vitreoretinal surgery, in particular for the management of complex vitreoretinal diseases. However, their use is not without complications, which are potentially severe. Consequently, a growing interest has been devoted to the biocompatibility of these compounds and the adequacy of current regulations that should guarantee their safety. Obviously, an updated knowledge on research findings and potential risks associated to the use of intraocular liquid compounds is essential, not only for vitreoretinal surgeons, but also for any ophthalmologist involved in the management of patients receiving intraocular liquid tamponades. In light of this, the review provides a comprehensive characterisation of intraocular liquid tamponades, in terms of physical and chemical properties, current clinical use and possible complications. Moreover, this review focuses on the safety profile of these compounds, summarising the existing regulation and the available evidence on their biocompatibility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.