ArticleJournal of perinatology : official journal of the California Perinatal Association2021
Sex differences in postnatal weight gain trajectories of extremely preterm newborns.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05515614 (Targeted Nutrition for Moderate to Late Preterm Infants), which is not on this map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Targeted Nutrition for Moderate to Late Preterm Infants
Who cites it
7 citing papers in PubMed.
- Early Human Milk Fortification in Infants Born Extremely Preterm: A Randomized Trial.Pediatrics · 2023Trial
- Postnatal growth trajectories of very preterm appropriate-for-gestational-age infants from term-equivalent age to 6 years.Pediatric research · 2026Article
- Determinants of growth parameters at 12-month corrected age among very preterm infants in China: a retrospective cohort study.Frontiers in pediatrics · 2026Article
- Sex-differences in Mothers' own milk and neurodevelopmental outcomes in preterm infants.Frontiers in pediatrics · 2025Article
- Expected and Desirable Preterm and Small Infant Growth Patterns.Advances in nutrition (Bethesda, Md.) · 2024Review
- A comparative study of postnatal anthropometric growth in very preterm infants and intrauterine growth.Nature communications · 2023Article
- Oxygenation index in the first three weeks of life is a predictor of bronchopulmonary dysplasia grade in very preterm infants.BMC pediatrics · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveBoth postnatal growth and sex play a crucial role in long-term outcomes of extremely preterm newborns (EPNs), but the relationship between sex and postnatal growth is not clear. This study aims to assess sex differences in weight trajectories. STUDY
designWeight data in the first 200 days of life from 4327 EPNs were used for generalized additive mixed modeling. We considered gestational age and sex as fixed-effects, and included random intercepts and random slopes for postnatal age. We assessed interactions between fixed-effects and postnatal age.
resultsMale EPNs had higher predicted weight trajectories than females. Weight z-score trajectories decreased in both sexes before term-equivalent age comparably, but females showed faster increases afterward. Although weight gain velocity was comparable between both sexes, weight gain velocity in male EPNs was lower compared to the corresponding reference values from the 2013 Fenton growth charts, which explained slower z-score rises.
conclusionSex disparity exists in postnatal weight gain trajectories of EPNs after reaching the term-equivalent age.
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Registered trials
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