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ArticleJournal of perinatology : official journal of the California Perinatal Association2021

Neurodevelopmental outcomes of singleton large for gestational age infants <29 weeks' gestation: a retrospective cohort study.

Deepika Rustogi, Anne Synnes, Belal Alshaikh, Shabih Hasan, Christine Drolet, Edith Masse, Prashanth Murthy, Prakesh S Shah, Kamran Yusuf, Canadian Neonatal Network and the Canadian Neonatal Follow-Up Program

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. [Neuropsychological development of large for gestational age infants at the age of 12 months].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Article
  4. Article
  5. Measuring intrauterine growth in healthy pregnancies using quantitative magnetic resonance imaging.Journal of perinatology : official journal of the California Perinatal Association · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Deepika RustogiSection of Neonatology, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Alberta, Canada.
Anne SynnesDivision of Neonatology, Department of Pediatrics, University of British Columbia, Vancouver, Canada.ORCID http://orcid.org/0000-0002-6917-0978
Belal AlshaikhSection of Neonatology, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Alberta, Canada.
Shabih HasanSection of Neonatology, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Alberta, Canada.
Christine DroletCHU de Quebec, University of Laval, Quebec, Canada.
Edith MasseCHU de Sherbrooke, University of Sherbrooke, Quebec, Canada.
Prashanth MurthySection of Neonatology, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Alberta, Canada.
Prakesh S ShahPediatrics, University of Toronto, Toronto, Canada.ORCID http://orcid.org/0000-0002-9920-0488
Kamran YusufSection of Neonatology, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Alberta, Canada. kyusuf@ucalgary.ca.ORCID http://orcid.org/0000-0001-5270-5326
Canadian Neonatal Network and the Canadian Neonatal Follow-Up Program

Funding

CIHR
6 · The paper itself

Abstract

objectiveTo compare neurodevelopmental outcomes of large and appropriate for gestational age (LGA, AGA) infants <29 weeks' gestation at 18-24 months of corrected age. STUDY

designRetrospective cohort study using the Canadian Neonatal Network and Canadian Neonatal Follow-Up Network databases. Primary outcome was a composite of death or significant neurodevelopmental impairment (NDI), defined as severe cerebral palsy, Bayley III cognitive, language and motor scores of <70, need for hearing aids or cochlear implant and bilateral visual impairment. Univariate and multivariable logistic analyses were applied for outcomes.

resultsThe study cohort comprised 170 LGA and 1738 AGA infants. There was no difference in significant NDI or individual components of the Bayley III between LGA and AGA groups. LGA was associated with the increased risk of death by follow-up, 44/170 (25.9%) vs. 320/1738 (18.4%) (aOR: 1.60 95% CI: 1.00-2.54).

conclusionsRisk of NDI was similar between LGA and AGA infants.

Indexed as

Gestational AgeCanadaFemaleHumansInfantInfant, NewbornPregnancyRetrospective Studies

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.